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Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations

Membrane transporters are of vital importance for cells. They mediate the flux of many substances through the plasma membrane. In this book, the transporters for organic cations, a special class of membrane transporters, are presented. Transporters belonging to this class are important because they...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2022
Soggetti:
transporters
endogenous metabolism
functional subgroups
SLC22
remote sensing and signaling
drug transporters
gut microbiome
chronic kidney disease
solute carrier 22 (SLC22)
Remote Sensing and Signaling Theory
interorgan communication
organic anion transporter
organic cation transporter
SLC22A15
SLC22A16
SLC22A18
kidney
Malpighian tubule
TCGA
human pathology atlas
gene ontology
organic cations
transport
kidneys
regulation
Nuclear receptor
renal excretion
bile acids
organic cation transporters
drug disposition
genetic polymorphisms
drug-induced kidney injury
nephrotoxicity
RA
Tofacitinib
Baricitinib
MATE1
solute carrier (SLC) family
OCT1
SLC22A1
species differences
drugs
pesticides
cisplatin nephrotoxicity
PPAR-alpha
organic transporters
serotonin transporter
plasma membrane monoamine transporter
ketamine
isoflurane
serotonin clearance
antidepressant-like activity
chronoamperometry
tail suspension test
forced swim test
hepatotoxicity
solute carrier
pulmonary drug delivery
SLC22A1–5
lung epithelium
drug uptake
β2-agonists
chronic lung diseases
anticholinergics
trospium
OCT
MATE
drug excretion
drug transport
n/a
thema EDItEUR::M Medicine and Nursing
Accesso online:ONIX_20220111_9783036505626_212
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