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Drug Metabolism/Transport and Pharmacokinetics

This book serves to highlight the pharmacokinetics/drug–drug interactions and mechanistic understanding in relation to the drug-metabolizing enzymes and drug transporters.This book presents a series of drug metabolism and transport mechanisms that govern the pharmacokinetic features of therapeutic d...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2022
Soggetti:
tofacitinib
dose-dependent pharmacokinetics
hepatic and intestinal first-pass effect
rats
catalposide
in vitro human metabolism
UDP-glucuronosyltransferase
sulfotransferase
carboxylesterase
celecoxib
drug–drug interaction
fluorescence
HPLC
metabolism
repaglinide
HSG4112
anti-obesity agent
stereoselectivity
pharmacokinetics
compound K
protopanaxadiol (PPD)
biliary excretion
intestinal metabolism
Carthamus tinctorius extract
notoginseng total saponins
comparative pharmacokinetic study
large volume direct injection
compatibility mechanism
mertansine
human hepatocytes
cytochrome P450
UDP-glucuronosyltransferases
sodium-glucose cotransporter 2 (SGLT2) inhibitors
DWP16001
kidney distribution
inhibition mode
diabetes
transporter-enzyme interplay
influx transporter
efflux transporter
physiologically based pharmacokinetic model
cytochrome P450 enzymes
tiropramide
healthy Korean subjects
modeling
population pharmacokinetic
quercetin
breast cancer resistance protein
inhibitor
prazosin
sulfasalazine
kinetic analysis
food–drug interactions
Caco-2
EpiIntestinal
first-pass
P-gp
BCRP
drug transporter
CYP3A4
oral availability
automatization
drug absorption
drug dosing
head-and-neck cancer
real-time measurements
taxanes
tissue engineering
UHPLC-MS/MS
metformin
verapamil
drug interaction
organic cation transporter 2
renal excretion
acute renal failure
gentamicin
cisplatin
hepatic CYP3A1(23)
creatinine clearance
renal clearance
nonrenal clearance
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries
Accesso online:ONIX_20220111_9783036524597_902
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ONIX_20220111_9783036524597_902

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