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Hedgehog Signaling in Organogenesis and Tumor Microenvironment

The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Cyp26 enzymes
congenital anomalies
CRE/LoxP
hedgehog signaling
mouse models
retinoic acid
smoothened
sonic hedgehog
sonic hedgehog (SHH)
oral squamous cell carcinoma (OSCC)
tumor microenvironment (TME)
tumor-associated macrophages (TAMs)
cancer-associated fibroblasts (CAFs)
tumor-associated angiogenesis
hedgehog
growth plate
endochondral ossification
chondrocyte
osteoblast
bone disease
TMJ
synovial joint
articular disc
Ihh
PTHrP
osteoarthritis
epithelial–mesenchymal interaction (EMI)
prostate cancer
external genitalia
androgen
basement membrane
bone morphogenetic protein
stem cell
animal experiment
fracture healing
cancer stem cells
hypospadias
urethra
penis
bone
hedgehog signalling
tooth development
epithelial and mesenchymal interaction
Gli1
mesenchymal stem cell
lineage tracing analysis
stem cell marker
n/a
thema EDItEUR::M Medicine and Nursing
Online Access:ONIX_20210501_9783039362608_913
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