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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy

In this book, we present a compilation of original research articles as well as review articles that are focused on improving our understanding of the molecular and cellular mechanisms by which cancer cells adapt to their microenvironment. These include the interplay between cancer cells and the sur...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
hypoxia
macrophages
colon cancer
tumor microenvironment
immune cell infiltration
prognosis
feline mammary carcinoma
PD-1
PD-L1
CTLA-4
TNF-α
biomarkers
immunotherapy
cancer
histone modification
inhibitor
KDM5B
molecular docking
repurposing
cancer acidity
hyperosmolarity
cross-presentation
tumour microenvironment
syngeneic model
prostate cancer
radiotherapy
preclinical modelling
myeloid-derived suppressor cells
biomarker
stroma
cancer-associated fibroblast (CAF)
extracellular matrix (ECM)
cytokine/chemokine
growth factors
pro- and anti-tumor immune cells
immunomodulatory roles
radiotherapy dose fractionation
radioresistance
radiosensitivity
breast cancer
S100A10 (p11)
tumor growth
tumor progression
metastasis
carcinoma
mammary gland
triple negative
pre-metastatic niche
pro-inflammatory cytokines
clinical trials
evolutionary therapy
darwinian evolution
cancer cells subpopulations
diclofenac
koningic acid
spheroid
3D co-culture
microenvironment
resistance
myeloid cells
cancer development
molecular subtypes of pancreatic cancer
chemotherapy response
pancreatic stellate cells
regulatory T cells
tumor-associated macrophages
myeloid derived suppressor cells
glioblastoma (GB)
Hypoxia Inducible Factor (HIF)
glioma stem cells (GSC)
oxidative stress
reactive oxygen species
plasmin
plasminogen
S100A10
uPA
uPAR
PAI-1
PAI-2
cancer stem cells
cancer recurrence
therapeutic resistance
signaling pathways
targeted therapy
head and neck cancer
lung cancer
bladder cancer
thema EDItEUR::M Medicine and Nursing
Online Access:ONIX_20220111_9783036516080_557
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