Hedgehog Signaling in Organogenesis and Tumor Microenvironment

The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with...

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Bibliographic Details
Format:	Online
Language:	English
Published:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:	Cyp26 enzymes congenital anomalies CRE/LoxP hedgehog signaling mouse models retinoic acid smoothened sonic hedgehog sonic hedgehog (SHH) oral squamous cell carcinoma (OSCC) tumor microenvironment (TME) tumor-associated macrophages (TAMs) cancer-associated fibroblasts (CAFs) tumor-associated angiogenesis hedgehog growth plate endochondral ossification chondrocyte osteoblast bone disease TMJ synovial joint articular disc Ihh PTHrP osteoarthritis epithelial–mesenchymal interaction (EMI) prostate cancer external genitalia androgen basement membrane bone morphogenetic protein stem cell animal experiment fracture healing cancer stem cells hypospadias urethra penis bone hedgehog signalling tooth development epithelial and mesenchymal interaction Gli1 mesenchymal stem cell lineage tracing analysis stem cell marker n/a thema EDItEUR::M Medicine and Nursing
Online Access:	ONIX_20210501_9783039362608_913
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Hedgehog Signaling in Organogenesis and Tumor Microenvironment

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