Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to t...
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| Główni autorzy: | , |
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| Format: | Online |
| Język: | angielski |
| Wydane: |
Frontiers Media SA
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | 18348 |
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