Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to t...
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| Materialtyp: | Online |
| Språk: | engelska |
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Frontiers Media SA
2021
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| Länkar: | 18348 |
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