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Glycan Diversity in Fungi, Bacteria and Sea Organisms

The cell surface of fungi, bacteria and sea organisms is highly glycosylated. These glycans are oligo- or polysaccharide molecules that can be secreted or attached to protein or lipids forming glycoconjugates. They present extraordinary structural diversity that could explain their involvement in ma...

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Hovedforfatter: Eliana Barreto-Bergter
Format: Online
Sprog:engelsk
Udgivet: Frontiers Media SA 2021
Fag:
Q1-390
RC109-216
Fungal pathogens
sea organisms
NMR
innate immunity
Mass Spectrometry
sulfated polysaccharides
carbohydrate-based drug development
Pattern Recognition Receptors
Plant-Bacterium Interaction
Adhesion
fungal glycoconjugates
bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
Online adgang:18329
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Summary:The cell surface of fungi, bacteria and sea organisms is highly glycosylated. These glycans are oligo- or polysaccharide molecules that can be secreted or attached to protein or lipids forming glycoconjugates. They present extraordinary structural diversity that could explain their involvement in many fundamental cellular processes, including growth, differentiation and morphogenesis. Considerable advances have been made on the structural elucidation of these glycans. Their primary structures were determined based on a combination of mass spectrometry and NMR spectroscopy techniques. The combination of these sensitive and powerful techniques has allowed us to increase our structural knowledge of a wide variety of glycans expressed by different fungi, bacteria and sea organisms.

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