Nutrition and Gene Interaction
Over the past 15 years, nutrigenomics has established the relationship between genes, nutrition, and disease. This exciting research area shows that nutrition is not just about preventing deficiencies; it can also prevent and treat chronic illnesses like diabetes, cancer, and neurodegenerative disor...
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| Format: | Online |
| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Teme: | |
| Online pristup: | https://directory.doabooks.org/handle/20.500.12854/170587 |
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| _version_ | 1863731293464821760 |
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| author | Bakovic, Marica |
| author_browse | Bakovic, Marica |
| author_facet | Bakovic, Marica |
| author_sort | Bakovic, Marica |
| collection | Directory of Open Access Books |
| description | Over the past 15 years, nutrigenomics has established the relationship between genes, nutrition, and disease. This exciting research area shows that nutrition is not just about preventing deficiencies; it can also prevent and treat chronic illnesses like diabetes, cancer, and neurodegenerative disorders. By identifying how nutrients modulate cellular signaling pathways, diet can be used as a first line of defense against these chronic illnesses. This research helps inform dietary recommendations at the individual level and guide public dietary guidelines to reduce the prevalence of chronic illness. This Special Issue compiles recent research on how nutrients impact genetic expression, using methods like transcriptomics, proteomics, and metabolomics. It presents nine studies exploring gene–diet interactions across various health outcomes, highlighting the promise and complexity of nutrigenomics. The key findings presented include the role of fermented foods in reducing the risk of non-alcoholic fatty liver disease, the influence of genetics on dietary needs and bone health, and the impact of early-life nutrition on long-term gene expression. The Special Issue also addresses the genetic regulation of liver, cardiovascular, and thyroid diseases, and the potential for personalized nutrition interventions to reduce disease risk. Overall, this reprint advocates for precision nutrition, leveraging genetic and epigenetic insights to create personalized dietary strategies for better health outcomes. |
| format | Online |
| id | doab-20.500.12854ir-170587 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1705872026-01-02T16:13:39Z Nutrition and Gene Interaction Bakovic, Marica non-alcoholic fatty liver disease sodium kimchi fermented vegetable stature GDF5 IGF-1R polygenic risk score in silico analysis energy intake childhood obesity DNA methylation epigenetics health disparities folate intake methyl donors dietary intake hypothyroidism white blood cell counts immunity inflammation diet pattern alcohol histone H3 acetylation p300 SIRT1 CCL2 promoter tributyrin CD36 CLOCK BMAL1 rs1761667 rs1984112 gene–diet interaction nutrition type 2 diabetes obesity nutrigenetics phytosterols SNVs campesterol sitosterol ABCG5/8 FTO haplotypes gene polymorphism genetic factors BMI metabolic syndrome diet quality lifestyle n-3 polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid alpha-linolenic acid mammary epithelial cells RNA-Seq n/a Over the past 15 years, nutrigenomics has established the relationship between genes, nutrition, and disease. This exciting research area shows that nutrition is not just about preventing deficiencies; it can also prevent and treat chronic illnesses like diabetes, cancer, and neurodegenerative disorders. By identifying how nutrients modulate cellular signaling pathways, diet can be used as a first line of defense against these chronic illnesses. This research helps inform dietary recommendations at the individual level and guide public dietary guidelines to reduce the prevalence of chronic illness. This Special Issue compiles recent research on how nutrients impact genetic expression, using methods like transcriptomics, proteomics, and metabolomics. It presents nine studies exploring gene–diet interactions across various health outcomes, highlighting the promise and complexity of nutrigenomics. The key findings presented include the role of fermented foods in reducing the risk of non-alcoholic fatty liver disease, the influence of genetics on dietary needs and bone health, and the impact of early-life nutrition on long-term gene expression. The Special Issue also addresses the genetic regulation of liver, cardiovascular, and thyroid diseases, and the potential for personalized nutrition interventions to reduce disease risk. Overall, this reprint advocates for precision nutrition, leveraging genetic and epigenetic insights to create personalized dietary strategies for better health outcomes. 2026-01-02T16:13:37Z 2026-01-02T16:13:37Z 2025 book 978-3-7258-4703-7 https://directory.doabooks.org/handle/20.500.12854/170587 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books https://mdpi.com/books/pdfview/book/11312 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-4704-4 10.3390/books978-3-7258-4704-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 978-3-7258-4703-7 150 CH open access |
| spellingShingle | non-alcoholic fatty liver disease sodium kimchi fermented vegetable stature GDF5 IGF-1R polygenic risk score in silico analysis energy intake childhood obesity DNA methylation epigenetics health disparities folate intake methyl donors dietary intake hypothyroidism white blood cell counts immunity inflammation diet pattern alcohol histone H3 acetylation p300 SIRT1 CCL2 promoter tributyrin CD36 CLOCK BMAL1 rs1761667 rs1984112 gene–diet interaction nutrition type 2 diabetes obesity nutrigenetics phytosterols SNVs campesterol sitosterol ABCG5/8 FTO haplotypes gene polymorphism genetic factors BMI metabolic syndrome diet quality lifestyle n-3 polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid alpha-linolenic acid mammary epithelial cells RNA-Seq n/a Bakovic, Marica Nutrition and Gene Interaction |
| title | Nutrition and Gene Interaction |
| title_full | Nutrition and Gene Interaction |
| title_fullStr | Nutrition and Gene Interaction |
| title_full_unstemmed | Nutrition and Gene Interaction |
| title_short | Nutrition and Gene Interaction |
| title_sort | nutrition and gene interaction |
| topic | non-alcoholic fatty liver disease sodium kimchi fermented vegetable stature GDF5 IGF-1R polygenic risk score in silico analysis energy intake childhood obesity DNA methylation epigenetics health disparities folate intake methyl donors dietary intake hypothyroidism white blood cell counts immunity inflammation diet pattern alcohol histone H3 acetylation p300 SIRT1 CCL2 promoter tributyrin CD36 CLOCK BMAL1 rs1761667 rs1984112 gene–diet interaction nutrition type 2 diabetes obesity nutrigenetics phytosterols SNVs campesterol sitosterol ABCG5/8 FTO haplotypes gene polymorphism genetic factors BMI metabolic syndrome diet quality lifestyle n-3 polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid alpha-linolenic acid mammary epithelial cells RNA-Seq n/a |
| topic_facet | non-alcoholic fatty liver disease sodium kimchi fermented vegetable stature GDF5 IGF-1R polygenic risk score in silico analysis energy intake childhood obesity DNA methylation epigenetics health disparities folate intake methyl donors dietary intake hypothyroidism white blood cell counts immunity inflammation diet pattern alcohol histone H3 acetylation p300 SIRT1 CCL2 promoter tributyrin CD36 CLOCK BMAL1 rs1761667 rs1984112 gene–diet interaction nutrition type 2 diabetes obesity nutrigenetics phytosterols SNVs campesterol sitosterol ABCG5/8 FTO haplotypes gene polymorphism genetic factors BMI metabolic syndrome diet quality lifestyle n-3 polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid alpha-linolenic acid mammary epithelial cells RNA-Seq n/a |
| url | https://directory.doabooks.org/handle/20.500.12854/170587 |
| work_keys_str_mv | AT bakovicmarica nutritionandgeneinteraction |