A Commemorative Issue in Honor of Centennial of the Discovery of Vitamin D-The Central Role of Vitamin D in Physiology

This reprint is about vitamin D, a molecule that can be absorbed from certain foods, such as fatty fish, which can also be produced endogenously when we expose our skin to sufficient doses of ultraviolet B radiation. When vitamin D is metabolized into 1,25(OH)2D3 (also called calcitriol), it acts as...

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Detalles Bibliográficos
Formato:	Online
Lenguaje:	inglés
Publicado:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Materias:	vitamin D VDR target genes chromatin epigenome transcriptome vitamin D signaling 25-hydroxyvitamin D 1,25-(OH)2D3 antitumor action breast cancer case-control studies colorectal cancer cohort studies ecological studies epidemiological studies randomized controlled trials UVB vitamin D receptor 3D structure structural analysis molecular recognition protein–ligand interactions coregulators acute myeloid leukemia blast 1,25-dihydroxyvitamin D analogs all-trans-retinoic acid differentiation immunomodulation evolution energy metabolism immune system calcium homeostasis migration of Homo sapiens influenza SARS-CoV-2 lung inflammation infantile hypercalcemia type 1 idiopathic infantile hypercalcemia CYP24A1 25-hydroxyvitamin D 24-hydroxylase hypercalcemia 24,25-dihydroxyvitamin D3 fracture repair diet transcellular absorption diffusion intestine homeostasis parathyroid hormone gestational diabetes preeclampsia preterm birth ovarian cancer vitamin D analogs vitamin D deficiency single high dose vitamin D3 supplementation proinflammatory cytokines IL6 IL8 TNF 25(OH)D3 brain development neuroprotection disease mechanisms genetic risk heritability personalized supplementation genome-wide association study Mendelian randomization lumisterol anti-inflammatory ACE2 Mpro RdRp month of birth muscle pregnancy older adults metabolites hybrids and VDR nonsecosteroidal ligands nongenomic response PDIA3 ultraviolet radiation megalin mitochondria vitamin D metabolism fibroblast growth factor-23 klotho 1α-hydroxylase RAAS systems biology cell differentiation prostate cancer n/a bone osteoblasts differentiation and mineralization McCollum sunlight rickets food fortification vitamin D2 vitamin D3 COVID-19 thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
Acceso en línea:	ONIX_20230405_9783036569185_181
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A Commemorative Issue in Honor of Centennial of the Discovery of Vitamin D-The Central Role of Vitamin D in Physiology

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