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The Pathophysiology of Preeclampsia and Eclampsia

Preeclampsia is a hypertensive disorder of pregnancy, diagnosed after the 20th week of gestation in women experiencing new-onset hypertension along with symptoms affecting the liver, kidneys, or brain. In some cases, women with preeclampsia develop novel seizures or unexplained coma, at which time t...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2023
Fag:
pre-eclampsia
eclampsia
pulmonary oedema
biobank
database
placental ischemia
seizure
ASIC2a
pregnancy
RUPP
pentylenetetrazol
melatonin
extracellular vesicle
exosome
preeclampsia
misfold proteins
endothelial cell activation
p21Cip1/CDKN1A
trophoblasts
hypoxia
trophoblast organoids
fusion
angiotensin II
AGTR1 (angiotensin II receptor type 1)
bradykinin
BDKRB2 (bradykinin receptor B2)
AT1R-B2R heteromer (protein complex formed of AT1R-B2R)
G-protein-coupled receptor
protein aggregation
ARRB (beta-arrestin)
early-onset preeclampsia
hemorheology
red blood cell aggregation
red blood cell deformability
erythrocyte
hypertension
IL-2
inflammation
oxidative stress
sFlt-1
NLRP3
nitric oxide
endothelial dysfunction
neuroinflammation
blood–brain barrier
cerebral edema
gestation
vessel
blood pressure
placenta
trophoblast
fetal growth restriction
maternal chronic venous disease (CVeD)
anti-inflammation
antioxidant
ischaemia
vitamin E
glucose transporter 9
GLUT9
uric acid
cardiac dysfunction
placental factors
activin A
G-protein-coupled receptors
GPCR
weighted gene correlation network analysis
WGCNA
blood-brain barrier
in vitro studies
cerebral biomarkers
NfL
tau
NSE
S100B
nebivolol
adrenoceptor
obesity
biomarkers
adipokines
adiponectin
leptin
ROS
angiogenic factors
hypoxia/reoxygenation
sFlT-1/PlGF ratio
primary trophoblast
thema EDItEUR::M Medicine and Nursing
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