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The Structural and Functional Study of Efflux Pumps Belonging to the RND Transporters Family from Gram-Negative Bacteria

Antimicrobial-resistant bacterial infections are a major and costly public health concern. Several pathogens are already pan-resistant, representing a major cause of mortality in patients suffering from nosocomial infections. Drug efflux pumps, which remove compounds from the bacterial cell, thereby...

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Kaydedildi:
Materyal Türü: Online
Dil:İngilizce
Baskı/Yayın Bilgisi: MDPI - Multidisciplinary Digital Publishing Institute 2022
Konular:
MdtF (YhiV)
multidrug resistance
RND-type efflux pump
dye accumulation
real-time efflux
pathogens
RND
evolution
efflux pump
adaptation
Aliarcobacter butzleri
RND efflux pumps
virulence
resistance
RND pump
dominant negative effect
assembly
protein-protein interaction
mutation
drug resistance
cystic fibrosis
prevalence of efflux resistance mechanisms
hospital acquired infections
antibiotic resistance
allostery
antimicrobial resistance
conformational changes
energetic transition
gram-negative bacteria
pump activation
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
Online Erişim:ONIX_20220506_9783036539461_112
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