Inhibiting PARP as a Strategic Target in Cancer
Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have...
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| Main Authors: | , |
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| Format: | Online |
| Sprog: | engelsk |
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Frontiers Media SA
2021
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| Online adgang: | 18342 |
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