Buchumschlag

Molecular and Cellular Mechanisms of Cancers

This reprint describes resistance to chemotherapy and radiotherapy, brain tumor stem cells, energy metabolism, epithelial-to-mesenchymal transition, immunotherapy, and reactive oxygen species phenotypes in glioblastoma.

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Bibliographische Detailangaben
Format:	Online
Sprache:	Englisch
Veröffentlicht:	MDPI - Multidisciplinary Digital Publishing Institute 2025
Schlagworte:	oxidative stress chaperone mediated autophagy (CMA) mitochondrial scavenger drug resistance reactive oxygen species (ROS), cell motility gliomas protein synthesis translation cap-dependent IRES astrocytoma glioblastoma serum proteins Protein Antibody Array decision tree survival glioblastoma stem cells (GSCs) epithelial-to-mesenchymal transition (EMT) markers GSC invasiveness transforming growth factor beta BzATP P2X7 receptor splice variants A and B tumor microenvironment exosomes microvesicles glioma stem cells immunotherapy resistance mechanisms programme death-1 immune checkpoint blockade glioblastoma (GBM) proteomics GBM cell-states recurrence tumour heterogeneity therapeutic targets WNK2 glioblastoma cell line autophagy inhibition autophagic flux glioma 5’-methylthioadenosine phosphorylase (MTAP) immunohistochemistry tumor biology proliferation migration invasion cancer stem cells M2 muscarinic receptors EGFR Notch cell cycle apoptosis radiotherapy membrane Hsp70 dose- and time-kinetics NK cell-based therapy non-coding RNA noncoding RNA BC200/miR-218-5p signaling circuit glioblastoma stem cells temozolomide resistance epithelial–mesenchymal transition (EMT) glioblastoma multiforme (GBM) 17β-estradiol (E2) estrogen receptors (ERs) adhesion arginine deprivation canavanine cancer cytoskeleton ER stress unfolded protein response IDH ADD3 high throughout techniques precision cerebral organoids nanomedicines astrocytes microglia lipocalin-2 inflammation glioblastomas hippo signaling pathway MST1/2 LATS1/2 YAP/TAZ TEADs energy metabolism glycolysis oxidative phosphorylation therapeutics gene expression profiling tumor model stem cell organoid heterogeneity immunosuppression microenvironment IDH1-mutation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics
Online-Zugang:	ONIX_20250220_9783725829347_496
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