Genetic and Epigenetic Regulations of Tumor Progression and Metastasis

Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therap...

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Бібліографічні деталі
Формат:	Online
Мова:	Англійська
Опубліковано:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Предмети:	prostate cancer metastasis epithelial-to-mesenchymal transition (EMT) partial-EMT (p-EMT) Zeb1 DNA methylation 5-azacytidine lung adenocarcinoma brain metastasis omics data analysis CDKN2A p16 invasive ductal breast cancer CDH1 gene EMT genes miRNA and mRNA expression E-cadherin HTR2B STAT proteins uveal melanoma promoter gene transcription PDAC inflammation hypoxia epithelial-to-mesenchymal transition cancer proliferation hepatocellular carcinoma engineered exosomes diagnostic biomarker cancer therapy angiogenesis pericytes adipose tissue cell adhesion endothelial cells breast cancer metastatic cascade intra-tumor heterogeneity mutational profile adaptive responses autophagy tumor mutational burden tumor microenvironment waterpipe smoke lung cancer n/a CYSLTR1 CYSLTR2 methylation prognosis colorectal cancer EMT thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Онлайн доступ:	ONIX_20230511_9783036571850_25
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Genetic and Epigenetic Regulations of Tumor Progression and Metastasis

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