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Genetic and Epigenetic Regulations of Tumor Progression and Metastasis

Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therap...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
prostate cancer
metastasis
epithelial-to-mesenchymal transition (EMT)
partial-EMT (p-EMT)
Zeb1
DNA methylation
5-azacytidine
lung adenocarcinoma
brain metastasis
omics data analysis
CDKN2A
p16
invasive ductal breast cancer
CDH1 gene
EMT genes
miRNA and mRNA expression
E-cadherin
HTR2B
STAT proteins
uveal melanoma
promoter
gene transcription
PDAC
inflammation
hypoxia
epithelial-to-mesenchymal transition
cancer proliferation
hepatocellular carcinoma
engineered exosomes
diagnostic biomarker
cancer therapy
angiogenesis
pericytes
adipose tissue
cell adhesion
endothelial cells
breast cancer
metastatic cascade
intra-tumor heterogeneity
mutational profile
adaptive responses
autophagy
tumor mutational burden
tumor microenvironment
waterpipe smoke
lung cancer
n/a
CYSLTR1
CYSLTR2
methylation
prognosis
colorectal cancer
EMT
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Online Access:ONIX_20230511_9783036571850_25
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