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Pathogenesis and Targeted Therapy of Epilepsy

Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respon...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2023
Soggetti:
3CAI
GRIA1
GRIA2
intractable epilepsy
PICK1
protein kinase C
pericytes
mural cells
cytokine
blood-brain barrier
neuroinflammation
3-phosphoinositide-dependent protein kinase-1
AKT
cyclosporin A
GluA1
GluR1
PDK1
refractory seizure
temporal lobe epilepsy
hippocampus
4-aminopyridine
epilepsy model
long-term potentiation
AMPA receptor
audiogenic epilepsy
rodents
fear reaction
behavior genetics
c-Fos
early gene activation
epileptogenesis
lipopolysaccharide
pentylenetetrazole
post-traumatic epilepsy
seizure susceptibility
traumatic brain injury
epilepsy
ghrelin
ghrelin receptor
anxiety
TRPV1 channels
neuronal activity
neuropsychiatric comorbidity
immunofluorescence
audiogenic kindling
acoustically evoked seizures
EACT
generalized tonic-clonic seizures
inherited epilepsy
TMEM1A channels
wild running seizures
astrocyte
ML365
pharmacoresistant epilepsy
cortical atrophy
hippocampal atrophy
intracerebral electrode
magnetic resonance imaging
posttraumatic epilepsy
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PH Physics
Accesso online:ONIX_20230307_9783036564364_22
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