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Hallmarks of Parkinson’s Disease

This book gathers a collection of review articles aiming to provide an update of the current knowledge on PD pathogenesis. It notably includes an overview of several key cellular dysfunctions underlying the etiology of Parkinson’s disease, including ER stress, mitophagy and alpha-synuclein-linked pa...

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Salvato in:
Natura: Online
Lingua:inglese
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2023
Soggetti:
Parkinson’s disease
unfolded protein response
reticulum endoplasmic
genetics
alpha-synuclein
prion-like spreading
cell-to-cell transfer
neurodegeneration
mitochondrial dysfunction
PINK1
neurons
astrocytes
microglia
α-synuclein
exocytosis
lipids
membranes
Parkinson disease
SNARE complex
synapse
vesicle fusion
therapeutic target
protein quality control
mitochondrial quality control
ubiquitin
alpha-syn
mitophagy
Parkin
mito-Keima
mito-QC
mito-SRAI
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Accesso online:ONIX_20230220_9783036550152_62
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ONIX_20230220_9783036550152_62

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