Novel Biomarkers of Gastrointestinal Cancer
Gastrointestinal (GI) cancer is a major cause of morbidity and mortality in the world. Since early diagnosis and optimal treatment selection are crucial to improving the prognosis of these diseases, the discovery of useful biomarkers has the potential to greatly reduce their burden. Recent technical...
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| Médium: | Online |
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| Jazyk: | angličtina |
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MDPI - Multidisciplinary Digital Publishing Institute
2023
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| On-line přístup: | ONIX_20230220_9783036549316_45 |
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| _version_ | 1863739348064665600 |
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| collection | Directory of Open Access Books |
| description | Gastrointestinal (GI) cancer is a major cause of morbidity and mortality in the world. Since early diagnosis and optimal treatment selection are crucial to improving the prognosis of these diseases, the discovery of useful biomarkers has the potential to greatly reduce their burden. Recent technical and mechanical developments have allowed for the detection of tiny differences in various factors modified in physical conditions, which could contribute to the discovery of novel biomarkers for some diseases.In this Special Issue, we aim to focus on novel biomarkers for GI cancers, including esophageal cancer, gastric cancer, colorectal cancer, liver cancer, pancreatic cancer and biliary cancer. In addition, any samples (tissue, blood, urine and feces) are useful as biomarker sources, although body-fluid-based biomarkers are promising as diagnostic biomarkers due to their noninvasiveness. This Special Issue aims to collect novel insights clarifying the current situation and future perspective in this field. |
| format | Online |
| id | doab-20.500.12854ir-97442 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-974422024-03-31T22:43:31Z Novel Biomarkers of Gastrointestinal Cancer Shimura, Takaya colorectal cancer advanced adenoma screening stool mRNA n/a cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Gastrointestinal (GI) cancer is a major cause of morbidity and mortality in the world. Since early diagnosis and optimal treatment selection are crucial to improving the prognosis of these diseases, the discovery of useful biomarkers has the potential to greatly reduce their burden. Recent technical and mechanical developments have allowed for the detection of tiny differences in various factors modified in physical conditions, which could contribute to the discovery of novel biomarkers for some diseases.In this Special Issue, we aim to focus on novel biomarkers for GI cancers, including esophageal cancer, gastric cancer, colorectal cancer, liver cancer, pancreatic cancer and biliary cancer. In addition, any samples (tissue, blood, urine and feces) are useful as biomarker sources, although body-fluid-based biomarkers are promising as diagnostic biomarkers due to their noninvasiveness. This Special Issue aims to collect novel insights clarifying the current situation and future perspective in this field. 2023-02-20T16:44:38Z 2023-02-20T16:44:38Z 2022 book ONIX_20230220_9783036549316_45 9783036549316 9783036549323 https://directory.doabooks.org/handle/20.500.12854/97442 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5937 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4932-3 10.3390/books978-3-0365-4932-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036549316 9783036549323 248 Basel open access |
| spellingShingle | colorectal cancer advanced adenoma screening stool mRNA n/a cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Novel Biomarkers of Gastrointestinal Cancer |
| title | Novel Biomarkers of Gastrointestinal Cancer |
| title_full | Novel Biomarkers of Gastrointestinal Cancer |
| title_fullStr | Novel Biomarkers of Gastrointestinal Cancer |
| title_full_unstemmed | Novel Biomarkers of Gastrointestinal Cancer |
| title_short | Novel Biomarkers of Gastrointestinal Cancer |
| title_sort | novel biomarkers of gastrointestinal cancer |
| topic | colorectal cancer advanced adenoma screening stool mRNA n/a cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | colorectal cancer advanced adenoma screening stool mRNA n/a cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20230220_9783036549316_45 |