Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications

Essential hypertension is still an important health care problem. It is necessary to investigate its mechanisms in animal models. The potential clinical importance of such experimental research might be expected. This Special Issue concerned several important topics. First, several studies focused o...

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Detalhes bibliográficos
Formato:	Online
Idioma:	inglês
Publicado em:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:	developmental origins of health and disease (DOHaD) gut microbiota hypertension short chain fatty acid oxidative stress probiotics prebiotics renin–angiotensin system fibroblast growth factor-23 left ventricular hypertrophy renin–angiotensin–aldosterone system losartan canrenone Hyp mice X-linked hypophosphatemia hairless SHRM cold acclimation cardiac Cx43 extracellular matrix thyroid hormones SHR sacubitril/valsartan ARNI ivabradine remodelling cardiac dysfunction fibrosis angiotensin II angiotensin 1-7 knock-out genome-editing SHRSP Dahl SS foetal programming of hypertension sympathetic neurotransmission sympathetic innervation vascular remodelling foetal undernutrition old SHR antihypertensive therapy blood pressure monitoring LV hypertrophy ECM markers cardiac fibrosis SHR-CRP SGLT-2 inhibitor gene expression age lipid metabolism nitric oxide l-NAME rostral ventrolateral medulla aging reactive oxygen species NADPH oxidase activator 1 mitochondria chloride calcium-activated chloride channel Na+–K+–2Cl− cotransporter 1 TMEM16A smooth muscle fetal undernutrition programming cross-fostering lactation period cardiovascular hypertrophy adipose tissue browning cardiovascular disease catecholamines liquid chromatography–tandem mass spectrometry SGLT-2 inhibition proteinuria uninephrectomized salt-loaded two-kidney one-clip hypertension fawn-hooded hypertensive rat ApoE KO apolipoprotein E knockout mice atherosclerosis Na,K-ATPase TCTP TCTP-overexpressing transgenic mice translationally controlled tumor protein TCTP-TG experimental hypertension bone rats taurine magnesium 24 h urine(24U) stroke-prone spontaneously hypertensive rat young SHR combination therapy treatment effect systolic blood pressure thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJD Cardiovascular medicine
Acesso em linha:	ONIX_20230202_9783036563183_167
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Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications

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