Mutagenesis and Mitochondrial-Associated Pathologies

Reactive oxygen species (ROS) and DNA double-strand breaks can result from mitochondrial defects and external sources, such as ionizing radiation. If not repaired properly, pathogenic mutations are generated. Human diseases resulting from inherited mitochondrial defects manifest in organs that physi...

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Bibliografiske detaljer
Format: Online
Sprog:engelsk
Udgivet: IntechOpen 2022
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Online adgang:ONIX_20220727_9781803551722_210
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