Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside

Nanomedicine is among the most promising emerging fields that can provide innovative and radical solutions to unmet needs in pharmaceutical formulation development. Encapsulation of active pharmaceutical ingredients within nano-size carriers offers several benefits, namely, protection of the therape...

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Bibliographische Detailangaben
Format:	Online
Sprache:	Englisch
Veröffentlicht:	MDPI - Multidisciplinary Digital Publishing Institute 2022
Schlagworte:	poly(lactic-co-glycolic acid) (PLGA) blood–brain barrier (BBB) current Good Manufacturing Practice (cGMP) Food and Drug Administration (FDA) nanotechnology PLGA nanoparticles neurodegenerative diseases drug delivery central nervous system neuroprotective drugs fluorescent labeling DiI coumarin 6 rhodamine 123 Cy5.5 quantum yield brightness stability of fluorescent label confocal microscopy intracellular internalization in vivo neuroimaging double-emulsion method dry powder inhalation antigen release porous PLGA particles microfluidics methotrexate chitosan PLA/PLGA sustained release micro-implant animal model minimally invasive drug delivery system nanoparticles poly (lactic-co-glycolic acid) (PLGA) microfluidic pharmacokinetics (PK) and biodistribution atorvastatin calcium poly(lactide-co-glycolide) polymeric nanoparticles carrageenan induced inflammation anti-inflammatory radiolabeled nanoparticles nuclear medicine photothermal therapy phthalocyanine SKOVip-kat Katushka TurboFP635 JO-4 PLGA orthotopic tumors 3D culture spheroids poly(lactic-co-glycolic acid) nanomedicine scale-up manufacturing clinical translation inline sonication tangential flow filtration lyophilization downstream processing H. pylori design of experiments poly(lactic-co-glycolic) acid size cancer chemoimmunotherapy immunogenic cell death immune checkpoint blockade PNA5 glycopeptide mas receptor angiotensin PLGA diblock copolymer ester and acid-end capped double emulsion solvent evaporation biocompatible biodegradable cardiovascular nanoparticle solid-state characterization in vitro drug release kinetics modeling PEGylation amine emulsion polyvinyl alcohol (PVA) Pluronic triblock copolymer trehalose sucrose Indomethacin solvents stabilizers morphology particle-size encapsulation drug release cytotoxicity thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
Online-Zugang:	ONIX_20220706_9783036544908_138
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Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside

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