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Recent Advances in Antibody Therapeutics

Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, “Recent Advances in Antibody Therapeutics”, presents leading-edge articles and reviews for discovery, development, and clinica...

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Formato: Online
Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2022
Assuntos:
interleukin 33
ST2 receptor
scFv
C2_2E12
bladder cancer
antibodies
immune checkpoint inhibitors
antibody-drug conjugates
sacituzumab govitecan
enfortumab vedotin
erdafitinib
cost-effectiveness
G protein-coupled receptor
membrane protein
antigen
therapeutic antibody
anti-angiogenesis
delta-like ligand
irinotecan
paclitaxel
VEGF
SARS-CoV-2
spike protein
receptor-binding domain
phage display
monoclonal antibody
cytomegalovirus
peptide/major histocompatibility complex class I complex
T-cell-receptor-like antibody
affinity maturation
yeast surface display
combinatorial antibody library
agonist antibody
cell fate
bispecific antibodies
bioassays
mechanisms of action
binding assays
potency assays
atherosclerosis
inflammation
antibody therapy
blood–brain barrier
antibody
pharmacokinetics
disposition
biochemical and physicochemical properties
Fc binding
receptor-mediated transcytosis
brain shuttle
molecular Trojan horse
transferrin
anti-cancer antibody
antibody engineering
biophysical properties
computational methods
research cell bank
antibody therapeutics
recombinant antibodies
intracellular antibodies
single-chain antibody fragment
nanobody
Human papillomaviruses
HPV oncoproteins
HPV-associated cancer
HPV cancer therapy
asthma
refractory asthma
biomarker
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PN Chemistry
Acesso em linha:ONIX_20220706_9783036543536_3
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Resumo:Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, “Recent Advances in Antibody Therapeutics”, presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodies

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