Chapter Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry

A characteristic of many proteoforms, derived from a single gene, is their similarity regarding the composition of atoms, making their analysis very challenging. Many overexpressed recombinant proteins are strongly associated with this problem, especially recombinant therapeutic glycoproteins from l...

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Hlavní autoři:	Heikaus, Laura, Schlüter, Hartmut, Nurul Hidayah, Siti, Gaikwad, Manasi
Médium:	Online
Jazyk:	angličtina
Vydáno:	InTechOpen 2021
Témata:	proteoforms, top-down mass spectrometry, therapeutic proteins, liquid chromatography, protein purification parameter screening, displacement chromatography thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
On-line přístup:	ONIX_20210602_10.5772/intechopen.89644_439
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!