Host-Directed Therapies for Tuberculosis

TB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entir...

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言語:英語
出版事項: MDPI - Multidisciplinary Digital Publishing Institute 2021
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collection Directory of Open Access Books
description TB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. This Special Issue will therefore cover most recent advances in the area of host-directed therapies for TB.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-693102024-03-28T03:33:11Z Host-Directed Therapies for Tuberculosis Venketaraman, Vishwanath Mycobacterium tuberculosis host-directed therapies immune responses tuberculosis lung cancer misdiagnosis invasive procedure revising antiplatelet aspirin immunomodulation survival Taiwan latent infection pulmonary rabbit iron supplementation pathology immune response gene expression Perls’ stain autophagy M. tb BCG vaccination immune exhaustion glutathione cytokines granulomas type 2 diabetes co-morbidities co-infections inflammation redox imbalance antioxidants thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences TB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. This Special Issue will therefore cover most recent advances in the area of host-directed therapies for TB. 2021-05-01T15:46:24Z 2021-05-01T15:46:24Z 2020 book ONIX_20210501_9783039435012_1056 9783039435012 9783039435029 https://directory.doabooks.org/handle/20.500.12854/69310 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3102 https://mdpi.com/books/pdfview/book/3102 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-502-9 10.3390/books978-3-03943-502-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039435012 9783039435029 120 Basel, Switzerland open access
spellingShingle Mycobacterium tuberculosis
host-directed therapies
immune responses
tuberculosis
lung cancer
misdiagnosis
invasive procedure
revising
antiplatelet
aspirin
immunomodulation
survival
Taiwan
latent infection
pulmonary
rabbit
iron supplementation
pathology
immune response
gene expression
Perls’ stain
autophagy
M. tb
BCG vaccination
immune exhaustion
glutathione
cytokines
granulomas
type 2 diabetes
co-morbidities
co-infections
inflammation
redox imbalance
antioxidants
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Host-Directed Therapies for Tuberculosis
title Host-Directed Therapies for Tuberculosis
title_full Host-Directed Therapies for Tuberculosis
title_fullStr Host-Directed Therapies for Tuberculosis
title_full_unstemmed Host-Directed Therapies for Tuberculosis
title_short Host-Directed Therapies for Tuberculosis
title_sort host directed therapies for tuberculosis
topic Mycobacterium tuberculosis
host-directed therapies
immune responses
tuberculosis
lung cancer
misdiagnosis
invasive procedure
revising
antiplatelet
aspirin
immunomodulation
survival
Taiwan
latent infection
pulmonary
rabbit
iron supplementation
pathology
immune response
gene expression
Perls’ stain
autophagy
M. tb
BCG vaccination
immune exhaustion
glutathione
cytokines
granulomas
type 2 diabetes
co-morbidities
co-infections
inflammation
redox imbalance
antioxidants
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet Mycobacterium tuberculosis
host-directed therapies
immune responses
tuberculosis
lung cancer
misdiagnosis
invasive procedure
revising
antiplatelet
aspirin
immunomodulation
survival
Taiwan
latent infection
pulmonary
rabbit
iron supplementation
pathology
immune response
gene expression
Perls’ stain
autophagy
M. tb
BCG vaccination
immune exhaustion
glutathione
cytokines
granulomas
type 2 diabetes
co-morbidities
co-infections
inflammation
redox imbalance
antioxidants
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20210501_9783039435012_1056