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Actinomycetes

Beyond being the most important natural compound source, actinomycetes are the origin of up to two-thirds of all clinically used antibiotics. Currently, new antimicrobials are urgently needed, as infections caused by antibiotic-resistant pathogens are on the rise. In the identification of new antibi...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Streptomyces
biogeography
comparative genomics
diversification
secondary metabolite biosynthetic gene clusters
SMGC
natural products
streptomyces
rishirilide
biosynthesis
polyketides
polynucleotide phosphorylase
ribonuclease
regulation
promoter
RNA decay
polyadenylation
(p)ppGpp
antibiotic
antibiotics
geomicrobiology
Illumina sequencing
microbiome diversity
Actinobacteria
Cave microbiology
secondary metabolite
rare Actinobacteria
Amycolatopsis
unculturability
siderophore
glycopeptide antibiotics
dbv cluster
regulatory genes
StrR
LAL
LuxR solo
dalbavancin
A40926
Streptomyces lividans
secretion pathways
secretory proteins
signal peptides
actinomycetes
teicoplanin
van resistance genes
Streptomyces tsukubaensis
tacrolimus
FK506
omics
screening
secondary metabolism
differentiation
elicitors
morphology
liquid cultures
metagenomics
rare actinomycetes
dereplication
metabolomics
genome mining
secondary metabolites
novel compounds
physicochemical screening
physical and chemical properties
structural diversity
biological activity
Actinoallomurus
antibiotics polyethers
lysolipin
minimal PKS II
cyclases
benz[a]naphthacene quinone
tridecaketide
aromatic polyketide
pentacyclic angular polyphenol
extended polyketide chain
actinobacteria
β-lactamase
resistance
β-lactamase inhibitor
polyketide synthases
acyltransferases
engineering
new bioactive compounds
symbiosis
drug discovery
chemical ecology
culture-based approaches
strain
specialized metabolites
biosynthetic gene cluster
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online Access:ONIX_20210501_9783039369102_774
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