Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment

ROS were long considered one of the key players in tissue injury. Indeed, overproduction of ROS results in oxidative stress, a process leading to the development of many pathological conditions. For the treatment of these conditions, the use of antioxidants was proposed. Over time, it was shown that...

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Format:	Online
Sprache:	Englisch
Veröffentlicht:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Schlagworte:	CTCL apoptosis cell viability c-FLIP XIAP artemisinin SH-SY5Y cells hippocampal neurons H2O2 AMPK pathway atherosclerosis sphingomyelin synthase 2 endothelial dysfunction endoplasmic reticulum stress β-catenin insulin resistance cancer cardiovascular disease neurodegenerative disorders exercise mitochondria oxidative stress PGC-1 Nrf2 UCPs ROS light DNA damage evolution D-box cavefish Spalax trimethylamine N-oxide cardiomyocytes cardiotoxicity mitochondrial membrane potential CORM-2 NADPH oxidase AP-1 HO-1 Renal cell carcinoma (RCC) reactive oxygen species (ROS) glutathione (GSH) metabolism cancer therapy clear cell RCC papillary RCC chromophobe RCC sarcopenia reactive oxygen species redox signaling antioxidant supplementation protein aggregation redox proteinopathy peroxiredoxins tumorigenesis ROS scavengers n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online-Zugang:	ONIX_20210501_9783039362820_719
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Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment

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