Mitogen Activated Protein Kinases

Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many di...

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Bibliographische Detailangaben
Format:	Online
Sprache:	Englisch
Veröffentlicht:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Schlagworte:	Rabdosia inflexa inflammation gastric ulcer cytokines MAPK NF-κB extracellular signal-regulated kinases 1/2 hyperoxia bronchopulmonary dysplasia HPAECs angiogenesis cell cycle SIRT1 oxidative stress psoriasis antimicrobial peptide cecropin A tight junction protein MEK/ERK signaling porcine intestinal epithelial cell extracellular signal-regulated kinase 5 (ERK5) Kv4.2 PC12 cells infantile myofibromatosis receptor tyrosine kinases platelet-derived growth factor receptor protein kinase inhibitors sunitinib erlotinib FR180204 U0126 targeted therapy apoptosis ERK1/2 JNKs mitochondrial dysfunction neurodegeneration neuro-inflammation p38 MAPKs Parkinson’s disease mitogen-activated protein kinases (MAPKs) MAPK kinetics osteoclast differentiation bone remodeling DAPK ERK p38 JNK mitogen-activated protein kinase pathway (MAPK pathway) protein tyrosine phosphatase interacting protein 51 (PTPIP51) protein-protein interaction (PPI) cancer signaling SR CR Compatibility T2DM metabolic profiling MAPK/PI3K/Akt signaling pathway reactive oxygen species PTPN6 SRC DOK4 MKK4 MKK7 p53 DUSP1 SIRT2 atherosclerosis aortic valve sclerosis aortic valve stenosis naphthalimide-metal complex conjugates N-heterocyclic carbene mitochondria ROS p38 MAPK cancer FGF-induced signaling FRS2 phosphorylation downregulation n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online-Zugang:	ONIX_20210501_9783039280704_389
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Zusammenfassung:	Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.

Mitogen Activated Protein Kinases

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