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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases

Natural-based biomolecules continuously play an important role in novel drug discovery for the treatment of chronic diseases. The development of natural peptide/protein-based, toxin-based, and antibody-based drugs can significantly improve the biomedical efficiency of disease-specific therapy. The f...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
DAPK1
SUMO
SENP
protein degradation
post-translational modification
amphibian Bowman-Birk inhibitor
Tat peptide
molecular cloning
antifungal
drug design
protease inhibitor
natural-based compound
anticancer therapy
lung cancer
survivin
apoptosis
STAT3
colorectal cancer
orientin
cell cycle arrest
Bcl-2 family proteins
Astragalus membranaceus
insulin
PI3K
AKT
PPARγ
PDX-1
Petasites japonicus
Asteraceae
lignan
anti-inflammation
NO
PGE2
iNOS
COX-2
molecular docking
peptides
kynurenines
binding affinity
μ-opioid receptor
pharmacophore
G-protein activation
fucoidan
PLGA
docetaxel
drug delivery system
anticancer therapy/cancer treatment
hIAPP
amyloidogenesis
insulin granules
endoplasmic reticulum
anionic lipids
F23R variant
β-sheet transitions
β-cell cytotoxicity
unfolded protein response
pomegranate
punicalagin
tannins
gingiva
fibroblasts
antioxidant
wound healing
branched-chain fatty acids
Conidiobolus heterosporus
peroxisome proliferator-activated receptor α
lipid metabolism
fatty acid oxidation
hepatocyte
n/a
thema EDItEUR::N History and Archaeology::NH History
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
Online Access:ONIX_20210501_9783036503868_266
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