The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, devastating and fatal disease characterized by selective loss of upper and lower motor neurons of the cerebral cortex, brainstem, spinal cord and muscle atrophy. In spite of many years of research, the pathogenesis of ALS is still not wel...

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Auteur principal:	Manoj Kumar Jaiswal
Format:	Online
Langue:	anglais
Publié:	Frontiers Media SA 2021
Sujets:	RC321-571 Q1-390 Mitochondria neurodegenerative disease Ca2+ signaling multidrug therapy Amyotrophic lateral sclerosis (ALS) Superoxide dismutase 1 (SOD1) Motor neuron disease (MND) excitotoxicity Riluzole multifactorial disease thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Accès en ligne:	22997
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