Recent Progress in Solid Dispersion Technology

Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recen...

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Đã lưu trong:
Chi tiết về thư mục
Tác giả chính: Kawakami, Kohsaku
Định dạng: Online
Ngôn ngữ:Tiếng Anh
Được phát hành: MDPI - Multidisciplinary Digital Publishing Institute 2021
Những chủ đề:
Truy cập trực tuyến:42550
Các nhãn: Thêm thẻ
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Miêu tả
Tóm tắt:Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.