Preclinical and clinical issues in Alzheimer's disease drug research and development

Alzheimer’s disease (AD) is a chronic neurodegenerative disorder characterized by progressive cognitive dysfunction and memory loss, inability to perform the activities of daily living and mood disorders. According to the so-called “amyloid cascade hypothesis”, amyloid-ß- peptide (Aß), produced by b...

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Main Authors: Silvana Gaetani, Cesare Mancuso
Formato: Online
Idioma:inglês
Publicado em: Frontiers Media SA 2021
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Acesso em linha:18188
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