The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick
The genetic code is one of the greatest discoveries of the 20th century as it is central to life itself. It is the algorithm that connects 64 RNA triplets to 20 amino acids, thus functioning as the Rosetta Stone of molecular biology. Following the discovery of the structure of DNA by James Watson an...
Պահպանված է:
| Հիմնական հեղինակ: | |
|---|---|
| Ձևաչափ: | Online |
| Լեզու: | անգլերեն |
| Հրապարակվել է: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
|
| Խորագրեր: | |
| Առցանց հասանելիություն: | 26465 |
| Ցուցիչներ: |
Չկան պիտակներ, Եղեք առաջինը, ով նշում է այս գրառումը!
|
| _version_ | 1863737817068208128 |
|---|---|
| author | Koji Tamura (Ed.) |
| author_browse | Koji Tamura (Ed.) |
| author_facet | Koji Tamura (Ed.) |
| author_sort | Koji Tamura (Ed.) |
| collection | Directory of Open Access Books |
| description | The genetic code is one of the greatest discoveries of the 20th century as it is central to life itself. It is the algorithm that connects 64 RNA triplets to 20 amino acids, thus functioning as the Rosetta Stone of molecular biology. Following the discovery of the structure of DNA by James Watson and Francis Crick in 1953, George Gamow organized the 20-member “RNA Tie Club” to discuss the transmission of information by DNA. Crick, Sydney Brenner, Leslie Barnett, and Richard Watts-Tobin first demonstrated the three bases of DNA code for one amino acid. The decoding of the genetic code was begun by Marshall Nirenberg and Heinrich Matthaei and was completed by Har Gobind Khorana. Then, finally, Brenner, Barnett, Eugene Katz, and Crick placed the last piece of the jigsaw puzzle of life by proving that UGA was a third stop codon. In the mid-1960s, Carl Woese proposed the “stereochemical hypothesis”, which speculated that the genetic code derives from a type of codon–amino acid-pairing interaction. The origin and evolution of the genetic code remains a mystery despite numerous theories and attempts to understand these. In this Special Issue, experts in the field present their thoughts and views on this topic. Because 2016 commemorated the 100th anniversary of the birth of Francis Crick, the Guest Editor of this Special Issue also dedicates all articles included herein to the memory of Francis Crick. |
| format | Online |
| id | doab-20.500.12854ir-55430 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-554302024-04-05T12:35:04Z The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick Koji Tamura (Ed.) QH426-470 QH301-705.5 Genetic code Specificity Codon Amino acid Francis Crick tRNA Stereochemistry Frozen accident Aminoacyl-tRNA synthetase Anticodon thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) The genetic code is one of the greatest discoveries of the 20th century as it is central to life itself. It is the algorithm that connects 64 RNA triplets to 20 amino acids, thus functioning as the Rosetta Stone of molecular biology. Following the discovery of the structure of DNA by James Watson and Francis Crick in 1953, George Gamow organized the 20-member “RNA Tie Club” to discuss the transmission of information by DNA. Crick, Sydney Brenner, Leslie Barnett, and Richard Watts-Tobin first demonstrated the three bases of DNA code for one amino acid. The decoding of the genetic code was begun by Marshall Nirenberg and Heinrich Matthaei and was completed by Har Gobind Khorana. Then, finally, Brenner, Barnett, Eugene Katz, and Crick placed the last piece of the jigsaw puzzle of life by proving that UGA was a third stop codon. In the mid-1960s, Carl Woese proposed the “stereochemical hypothesis”, which speculated that the genetic code derives from a type of codon–amino acid-pairing interaction. The origin and evolution of the genetic code remains a mystery despite numerous theories and attempts to understand these. In this Special Issue, experts in the field present their thoughts and views on this topic. Because 2016 commemorated the 100th anniversary of the birth of Francis Crick, the Guest Editor of this Special Issue also dedicates all articles included herein to the memory of Francis Crick. 2021-02-11T21:54:16Z 2021-02-11T21:54:16Z 2018-04-06 13:38:32 2018 book 26465 9783038427698 9783038427704 https://directory.doabooks.org/handle/20.500.12854/55430 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/568 http://www.mdpi.com/books/pdfview/book/568 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03842-770-4 10.3390/books978-3-03842-770-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038427698 9783038427704 X, 192 open access |
| spellingShingle | QH426-470 QH301-705.5 Genetic code Specificity Codon Amino acid Francis Crick tRNA Stereochemistry Frozen accident Aminoacyl-tRNA synthetase Anticodon thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) Koji Tamura (Ed.) The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick |
| title | The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick |
| title_full | The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick |
| title_fullStr | The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick |
| title_full_unstemmed | The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick |
| title_short | The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick |
| title_sort | origin and evolution of the genetic code 100th anniversary year of the birth of francis crick |
| topic | QH426-470 QH301-705.5 Genetic code Specificity Codon Amino acid Francis Crick tRNA Stereochemistry Frozen accident Aminoacyl-tRNA synthetase Anticodon thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) |
| topic_facet | QH426-470 QH301-705.5 Genetic code Specificity Codon Amino acid Francis Crick tRNA Stereochemistry Frozen accident Aminoacyl-tRNA synthetase Anticodon thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) |
| url | 26465 |
| work_keys_str_mv | AT kojitamuraed theoriginandevolutionofthegeneticcode100thanniversaryyearofthebirthoffranciscrick AT kojitamuraed originandevolutionofthegeneticcode100thanniversaryyearofthebirthoffranciscrick |