Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases

Cytotoxic lymphocytes, comprised of NK cells and cytotoxic T cells, play a pivotal role in immune defense. By directed release of perforin-containing lytic granules, NK and cytotoxic T cells can eradicate pathogen-infected, tumorigenic, and otherwise stressed cells. By the virtue of cytokine and che...

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Main Authors: Konrad Krzewski, Yenan Bryceson
Formato: Online
Idioma:inglês
Publicado em: Frontiers Media SA 2021
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Acesso em linha:17831
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