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Major Histocompatibility Complex (MHC) in Health and Disease

The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually...

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Saved in:
Main Authors: Shiina, Takashi, Dijkstra, Johannes M., Kulski, Jerzy K.
Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2021
Fag:
QH301-705.5
Q1-390
HCP5
n/a
camels
MHC
STK19
major histocompatibility complex
human papillomavirus (HPV)
T-cell receptor
T1DGC
bottleneck
micro-mini-pigs
life history
computational analysis
hepatocellular carcinoma
phase
Bactrian camel
NSDK
melanoma
antigen
autoimmune disease
RD
selection
disease resistance
autoimmunity
ancestral haplotype
Ski complex
DXO
high-throughput sequencing
conservation genetics
SVA
lncRNA
ankylosing spondylitis
MHC genes
viral peptides
competing endogenous RNA (ceRNA)
astrogliosis
birds
long-fragment super haplotype
SNP
RLR
HLA polymorphism
5??3? RNA decay
expression
3??5? mRNA turnover
orthology
long-read sequencing
disease association
dromedary
polyomavirus
MHC-II-associated sperm-egg recognition
experimental medicine
single nucleotide polymorphism (SNP)
fish
SKIV2L
production trait
molecular dynamics simulation
Macaca fascicularis
human endogenous retrovirus (HERV)
concerted evolution
polymorphism
Old World camels
MHC polymorphism
protocol
nonclassical
gene duplication
microglial reaction
human leukocyte antigen-E
SKI2W
quantitative trait loci (QTL) studies
antiviral immunity
human immunodeficiency virus (HIV)
founder effect
giant panda
domain movements
BK virus
promoter-proximal transcriptional pause
type 1 diabetes (T1D)
RP1
miR1236
KIR
synaptic covering
swine leukocyte antigen
cynomolgus macaque
HLA
kidney transplantation
?2m knockout mice
DOM3Z
interferon ?
ethnic populations in China
ecology
KIR–HLA pairs
exosomes
major histocompatibility complex (MHC)
MHC-I-based mother-fetus recognition
RNA quality control
autoimmune diseases
NELF-E
haplotype
genetic drift
evolution
nonhuman primate models
HLA-B27
PNS/CNS interface
risk genes
pedigree
MHC-I- and MHC-II-dependent inter-individual recognition
regulation
crested ibis
reproductive performance
nephropathy
cancer
nuclear kinase
trichohepatoenteric syndrome
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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