Effects of Ionizing Radiation in Cancer Radiotherapy

For a long time, it was widely accepted that the biological effects of ionizing radiation such as cell death, DNA damage, and mutagenesis result from the direct ionization of cell structures, particularly DNA, or from indirect damage through reactive oxygen species produced by water radiolysis. This...

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Bibliographic Details
Format:	Online
Language:	English
Published:	MDPI - Multidisciplinary Digital Publishing Institute 2025
Subjects:	chondrosarcoma bystander signaling proteomic analysis secretome stress granules bystander effect exosomes ionizing radiation non-targeted effects of radiation replication stress radioresistance radiosensitivity cancer stem cells epithelial mesenchymal transition polyploid/multinucleated giant cancer cells proton therapy beam clustered DNA damage linear energy transfer (LET) Agarose Gel Electrophoresis (AGE) Atomic Force Microscopy (AFM) damage biomarkers scavenging capacity biodosimetry glioblastoma multiforme multinucleated giant cancer cell senescent tumor cells (STC) stress-induced premature senescence (SIPS) senescence-associated secretory phenotype (SASP) non-small cell lung cancer DNA repair transcriptomics gene expression cytogenetic biodosimetry radioprotection telomere centromere chromosomal instability radiotherapy radiation-induced BCC low-dose effects ATM-NF-kb signaling PINK1 gene microRNA biomarkers proton radiotherapy pediatric oncology HARMONIC project congenital heart disease cardiac catheterization radiation biomarkers bone marrow ionising radiation extracellular vesicles miRNA content proteome pathway analysis bystander effects thema EDItEUR::M Medicine and Nursing
Online Access:	ONIX_20250812T095121_9783725833863_185
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Effects of Ionizing Radiation in Cancer Radiotherapy

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