Iron Intake and Human Health

Iron deficiency (ID) and iron deficiency anemia (IDA) are global problems that affect more than 2 billion people, accounting for significant mortality annually worldwide. Children, girls, and women of reproductive age are particularly vulnerable to ID and IDA due to their high physiological iron dem...

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প্রকাশিত: MDPI - Multidisciplinary Digital Publishing Institute 2024
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অনলাইন ব্যবহার করুন:ONIX_20240514_9783036596402_99
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collection Directory of Open Access Books
description Iron deficiency (ID) and iron deficiency anemia (IDA) are global problems that affect more than 2 billion people, accounting for significant mortality annually worldwide. Children, girls, and women of reproductive age are particularly vulnerable to ID and IDA due to their high physiological iron demands. The consequences of IDA include deleterious effects on cognition, mental function, work performance, and pregnancy outcomes. The causes of IDA include low iron intake and poor iron bioavailability from ingested foods. Inflammation and human diseases that are associated with high levels of hepcidin (the hormone that regulates the iron efflux protein, ferroportin) due to mutation in a serine protease, TMPRSS6, can also cause iron deficiency. Practical strategies aimed at preventing anemia include iron supplementation and the fortification of foods. Novel iron compounds that are aimed at averting complications such as irritation and inflammation of the gastrointestinal tract are being synthesized. On the other hand, concerns about the mandatory iron fortification of foods in segments of the population that are predisposed to the consequences of excess tissue iron toxicity can be addressed through administration of iron chelators.
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1374972024-05-14T13:18:33Z Iron Intake and Human Health Latunde-Dada, Gladys Oluyemisi iron citrate (II) food supplement nutraceuticals iron deficiency anaemia dietary iron intake heme iron nonheme iron metabolic syndrome population-based study DMT1 knockout ferrous bisglycinate ferrous sulfate transport intestinal ferropenic anaemia endocrine regulators body composition energy expenditure alginate iron microbiome ROS prebiotic diabetes mellitus type 1 pregnancy fetal programming infant newborn anemia TMPRSS6 iron intake children Indonesia Myanmar sub-clinical inflammation growth development premature risk assessment probabilistic model second-order Monte Carlo simulation DALY n/a thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics Iron deficiency (ID) and iron deficiency anemia (IDA) are global problems that affect more than 2 billion people, accounting for significant mortality annually worldwide. Children, girls, and women of reproductive age are particularly vulnerable to ID and IDA due to their high physiological iron demands. The consequences of IDA include deleterious effects on cognition, mental function, work performance, and pregnancy outcomes. The causes of IDA include low iron intake and poor iron bioavailability from ingested foods. Inflammation and human diseases that are associated with high levels of hepcidin (the hormone that regulates the iron efflux protein, ferroportin) due to mutation in a serine protease, TMPRSS6, can also cause iron deficiency. Practical strategies aimed at preventing anemia include iron supplementation and the fortification of foods. Novel iron compounds that are aimed at averting complications such as irritation and inflammation of the gastrointestinal tract are being synthesized. On the other hand, concerns about the mandatory iron fortification of foods in segments of the population that are predisposed to the consequences of excess tissue iron toxicity can be addressed through administration of iron chelators. 2024-05-14T13:18:28Z 2024-05-14T13:18:28Z 2024 book ONIX_20240514_9783036596402_99 9783036596402 9783036596419 https://directory.doabooks.org/handle/20.500.12854/137497 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/8655 https://mdpi.com/books/pdfview/book/8655 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9641-9 10.3390/books978-3-0365-9641-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036596402 9783036596419 160 open access
spellingShingle iron citrate (II)
food supplement
nutraceuticals
iron deficiency
anaemia
dietary iron intake
heme iron
nonheme iron
metabolic syndrome
population-based study
DMT1
knockout
ferrous bisglycinate
ferrous sulfate
transport
intestinal
ferropenic anaemia
endocrine regulators
body composition
energy expenditure
alginate
iron
microbiome
ROS
prebiotic
diabetes mellitus
type 1
pregnancy
fetal programming
infant
newborn
anemia
TMPRSS6
iron intake
children
Indonesia
Myanmar
sub-clinical inflammation
growth
development
premature
risk assessment
probabilistic model
second-order Monte Carlo simulation
DALY
n/a
thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics
Iron Intake and Human Health
title Iron Intake and Human Health
title_full Iron Intake and Human Health
title_fullStr Iron Intake and Human Health
title_full_unstemmed Iron Intake and Human Health
title_short Iron Intake and Human Health
title_sort iron intake and human health
topic iron citrate (II)
food supplement
nutraceuticals
iron deficiency
anaemia
dietary iron intake
heme iron
nonheme iron
metabolic syndrome
population-based study
DMT1
knockout
ferrous bisglycinate
ferrous sulfate
transport
intestinal
ferropenic anaemia
endocrine regulators
body composition
energy expenditure
alginate
iron
microbiome
ROS
prebiotic
diabetes mellitus
type 1
pregnancy
fetal programming
infant
newborn
anemia
TMPRSS6
iron intake
children
Indonesia
Myanmar
sub-clinical inflammation
growth
development
premature
risk assessment
probabilistic model
second-order Monte Carlo simulation
DALY
n/a
thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics
topic_facet iron citrate (II)
food supplement
nutraceuticals
iron deficiency
anaemia
dietary iron intake
heme iron
nonheme iron
metabolic syndrome
population-based study
DMT1
knockout
ferrous bisglycinate
ferrous sulfate
transport
intestinal
ferropenic anaemia
endocrine regulators
body composition
energy expenditure
alginate
iron
microbiome
ROS
prebiotic
diabetes mellitus
type 1
pregnancy
fetal programming
infant
newborn
anemia
TMPRSS6
iron intake
children
Indonesia
Myanmar
sub-clinical inflammation
growth
development
premature
risk assessment
probabilistic model
second-order Monte Carlo simulation
DALY
n/a
thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics
url ONIX_20240514_9783036596402_99