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Steroid Compounds with Potential Biological Activity

Steroids are a large group of compounds whose structure is based on a 17-carbon skeleton, with a specific cyclopentanoperhydrophenanthrene ring system. Natural steroids have been fine-tuned through evolution to build membranes; act as chemical messengers that regulate metabolic, immune and reproduct...

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Sparad:
Materialtyp: Online
Språk:engelska
Utgiven: MDPI - Multidisciplinary Digital Publishing Institute 2024
Ämnen:
4-azasteroids
4-azapregnenes
aldol condensation
molecular docking
antiproliferative activity
Paracaudina chilensis
Molpadida
triterpene glycosides
chilensosides
sea cucumber
cytotoxic activity
26-thiodiosgenin
thiol oxidation
sulfoxides
sulfones
sapogenins
steroids
antimicrobial activity
cytotoxicity
breast cancer
endocrine therapy
endocrine resistance
aromatase inhibitors
exemestane
oxymestane
anti-cancer properties
multi-target compounds
aromatase
estrogen receptor
androgen receptor
Chan–Lam reaction
diaryl ether
13α-estrone
antiproliferative effect
tubulin polymerization
molecular dynamics
oximes
chemistry
antitumor
anti-inflammatory
antibacterial
antifungal
antiviral
triterpenoids
isoprenoid lipids
anti-neoplastic
anti-fungal
anti-bacterial
anti-viral
fungal endophytes
plants
marine invertebrates
furanosteroids
fungi
marine organisms
diacetoxy-5α-cholestane
crystal structure HSA binding
multi-spectroscopy
DFT
steroid dimers
1,4-phenylene-linked dimers
montmorillonite
DHEA
cholesterol
cation channels
TRPML1
bioisostere
estrogens
ring cleavage
protective groups
pyridines
pyrimidines
cyclization
antimetabolites
cell growth inhibition
gene expression
HeLa cells
in vitro culture
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Länkar:ONIX_20240108_9783036596174_126
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