New Insights into Inflammatory Bowel Disease

The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknow...

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Đã lưu trong:
Chi tiết về thư mục
Định dạng: Online
Ngôn ngữ:Tiếng Anh
Được phát hành: IntechOpen 2023
Những chủ đề:
Truy cập trực tuyến:ONIX_20231201_9789535127550_464
Các nhãn: Thêm thẻ
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Miêu tả
Tóm tắt:The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.