Natural Polyphenols in Human Health
Polyphenols are natural phytochemicals recognized as one of the largest and most widespread classes of plant constituents occurring throughout the plant kingdom. Over the years, polyphenols have attracted the attention of the scientific community due to their potential health-promoting effects. Owin...
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| 言語: | 英語 |
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MDPI - Multidisciplinary Digital Publishing Institute
2023
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| オンライン･アクセス: | ONIX_20231130_9783036590769_284 |
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| description | Polyphenols are natural phytochemicals recognized as one of the largest and most widespread classes of plant constituents occurring throughout the plant kingdom. Over the years, polyphenols have attracted the attention of the scientific community due to their potential health-promoting effects. Owing to their several interesting properties, polyphenols have aroused considerable interest, shedding light on their chemistry, reactivity, biological properties and their beneficial effects on both plants and humans. As a result of these investigations, a huge number of research works have been reported on polyphenols. However, despite the voluminous literature studying polyphenols and their impact on human health, there are still many issues waiting to be explored in order to explain and elucidate the positive effects of polyphenols on human health. This Special Issue was intended to gather up-to-date knowledge related to the cutting-edge research in the broad scientific area of polyphenols, providing an opportunity to show the latest advances in the exploration of polyphenols and their health beneficial effects. The special issue was a great success with more than 50 published manuscripts covering various aspects related to polyphenols and their role in human health. We are confident that this Special Issue will be of great interest to the scientific community, and will contribute to the improvement of knowledge regarding the area of polyphenols, leading to a better understanding of their role in human health. |
| format | Online |
| id | doab-20.500.12854ir-128832 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1288322024-03-28T03:30:35Z Natural Polyphenols in Human Health Es-Safi, Nour Eddine polyphenolic curcumin cisplatin combination therapy breast cancer apoptosis gemini surfactant nanoparticles Mucuna pruriens seed neuroprotective activity Parkinson’s disease anti-acetylcholinesterase activity L-dopa Mitrephora sirikitiae anti-inflammation lignans polyphenols mRNA expression cytokines gemini curcumin colorectal cancer RNA sequencing PPI network differentially expressed genes Ericaceae LC–DAD/ESI–MS phenolic compounds flavonoids antioxidant activity Artemia salina Leach resveratrol hexavalent chromium 8-hydroxydeoxyguanosine adduct repair endogenous antioxidant system antigenotoxic Opuntia sp. prickly pear inflammation ginseng leaf far-infrared irradiation ginsenosides antioxidants health benefits polysaccharides freeze-drying spray-drying antidiabetic Averrhoa carambola L. dihydrochalcone flavone glycosides obesity Oxalidaceae type 2 diabetes Alchemilla viridiflora Rothm. SARS-CoV-2 COVID-19 spike glycoprotein neuropilin-1 in vitro in silico Origanum compactum HPLC-PDA-ESI/MS antibacterial activity bioactive compounds nutraceuticals phenols pomegranate peels phytochemical wistin NADES total polyphenolic content enzyme inhibition functional food natural medicine Alzheimer cholinesterase inhibitors Maqui platelets phenolic compounds and cardiovascular phenolic acids sinapic acid ACE inhibition hypertension endothelial dysfunction Graminex pollen hydroalcoholic extract oxidative stress gene expression TRPV1 pterostilbene antioxidant bioavailability cancer diabetes Nrf2 Rosmarinus officinalis chemical analysis glioblastoma rhabdomyosarcoma red onion phytochemicals H9c2 rat cardiomyoblast primary human fibroblasts blood disorder haemoglobin natural product nutraceutical nutritional disease lichens neuroprotection cetrarioid clade grape polyphenols sarcopenia skeletal muscle clinical trial R. conduplicans lichen secondary metabolites DNA damage α-glucosidase inhibition adlay adlay testa antiglycation phenolic acid grape pomace anti-inflammatory curcumin poly(glycerol sebacate) nanoparticles drug delivery system human cervical cancer baicalein mangiferin quercetin diabetes mellitus peripheral artery disease cardiovascular diseases Cyperus esculentus tiger nut metabolomics UHPLC-ESI-QTOF-MS/MS foodomics scopolamine memory impairments phenol compounds polydatin 3-O-β-d-resveratrol-glucopyranoside cervical cancer lung cancer ovarian cancer nanosuspension antioxidant properties LPS-induced inflammation NO-scavenging activity mountain tea Lamiaceae iridoids phenylethanoids ultrasound-assisted extraction melittoside ajugoside verbascoside ferulic acid apoptosis and cell cycle arrest anti-angiogenesis anti-metastasis synergism Cymbopogon schoenanthus hyaluronidase acetylcholinesterase neurodegeneration skin hair human health immobilized PTP1B drug screening cell surface display salvianolic acid B traditional Chinese medicine Salicornia extraction technologies agro-industrial by-products biological activity circular economy health effects re-integration waste management blood orange peels infrared-assisted extraction optimization Aflatoxin B1 Achillea millefolium bioaccessibility Caco-2 absorption in vitro digestion sterol regulatory element-binding protein 1 human oral squamous cell carcinoma autophagy epidermal fatty acid-binding protein lentil hull enzymatic hydrolysis microwave-assisted extraction oligosaccharides Alocasia gigantea hepatocellular carcinoma histopathology UHPLC–DAD–ESI–MS/MS Salvianolic acid B matrix metalloproteinase 9 gelatinase B MDA-MB-231 human breast cancer cells TIMP-1 agri-food wastes sustainability polyphenols bioavailability polyphenols activity cosmeceuticals nano-delivery health Lithocarpus litseifolius trilobatin phloridzin phloretin metabolic pathway bioactivity honey functional beverage characterization alcoholic beverage fermented beverage functional foods beneficial effects biological treatment bioreactors water aerobic granular sludge conventional active ted sludge biofilter photobioreactor membrane bioreactor bio-electrochemical systems chitosan Indian borage biotic elicitor insect-based foods Folin–Ciocalteu method phenols and flavonoids polyphenols bioactivity cereal pre-harvest sprouting antiradical capacity antitumor activity bee products phenylamides multivariate statistical analysis Juniperus sabina cupressuflavone intranasal pharmacokinetic motor coordination oregano box–behnken phenolics HPLC-PDA analysis UPLC-Q-TOF MS olive pomace PBMC immune gene expression HPLC-DAD metabolome phenolic bioaccessibility propolis total phenolic compounds antioxidant capacity UHPLC-DAD-ESI-MS thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Polyphenols are natural phytochemicals recognized as one of the largest and most widespread classes of plant constituents occurring throughout the plant kingdom. Over the years, polyphenols have attracted the attention of the scientific community due to their potential health-promoting effects. Owing to their several interesting properties, polyphenols have aroused considerable interest, shedding light on their chemistry, reactivity, biological properties and their beneficial effects on both plants and humans. As a result of these investigations, a huge number of research works have been reported on polyphenols. However, despite the voluminous literature studying polyphenols and their impact on human health, there are still many issues waiting to be explored in order to explain and elucidate the positive effects of polyphenols on human health. This Special Issue was intended to gather up-to-date knowledge related to the cutting-edge research in the broad scientific area of polyphenols, providing an opportunity to show the latest advances in the exploration of polyphenols and their health beneficial effects. The special issue was a great success with more than 50 published manuscripts covering various aspects related to polyphenols and their role in human health. We are confident that this Special Issue will be of great interest to the scientific community, and will contribute to the improvement of knowledge regarding the area of polyphenols, leading to a better understanding of their role in human health. 2023-11-30T20:56:54Z 2023-11-30T20:56:54Z 2023 book ONIX_20231130_9783036590769_284 9783036590769 9783036590776 https://directory.doabooks.org/handle/20.500.12854/128832 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8302 https://mdpi.com/books/pdfview/book/8302 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9077-6 10.3390/books978-3-0365-9077-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036590769 9783036590776 532 Basel open access |
| spellingShingle | polyphenolic curcumin cisplatin combination therapy breast cancer apoptosis gemini surfactant nanoparticles Mucuna pruriens seed neuroprotective activity Parkinson’s disease anti-acetylcholinesterase activity L-dopa Mitrephora sirikitiae anti-inflammation lignans polyphenols mRNA expression cytokines gemini curcumin colorectal cancer RNA sequencing PPI network differentially expressed genes Ericaceae LC–DAD/ESI–MS phenolic compounds flavonoids antioxidant activity Artemia salina Leach resveratrol hexavalent chromium 8-hydroxydeoxyguanosine adduct repair endogenous antioxidant system antigenotoxic Opuntia sp. prickly pear inflammation ginseng leaf far-infrared irradiation ginsenosides antioxidants health benefits polysaccharides freeze-drying spray-drying antidiabetic Averrhoa carambola L. dihydrochalcone flavone glycosides obesity Oxalidaceae type 2 diabetes Alchemilla viridiflora Rothm. SARS-CoV-2 COVID-19 spike glycoprotein neuropilin-1 in vitro in silico Origanum compactum HPLC-PDA-ESI/MS antibacterial activity bioactive compounds nutraceuticals phenols pomegranate peels phytochemical wistin NADES total polyphenolic content enzyme inhibition functional food natural medicine Alzheimer cholinesterase inhibitors Maqui platelets phenolic compounds and cardiovascular phenolic acids sinapic acid ACE inhibition hypertension endothelial dysfunction Graminex pollen hydroalcoholic extract oxidative stress gene expression TRPV1 pterostilbene antioxidant bioavailability cancer diabetes Nrf2 Rosmarinus officinalis chemical analysis glioblastoma rhabdomyosarcoma red onion phytochemicals H9c2 rat cardiomyoblast primary human fibroblasts blood disorder haemoglobin natural product nutraceutical nutritional disease lichens neuroprotection cetrarioid clade grape polyphenols sarcopenia skeletal muscle clinical trial R. conduplicans lichen secondary metabolites DNA damage α-glucosidase inhibition adlay adlay testa antiglycation phenolic acid grape pomace anti-inflammatory curcumin poly(glycerol sebacate) nanoparticles drug delivery system human cervical cancer baicalein mangiferin quercetin diabetes mellitus peripheral artery disease cardiovascular diseases Cyperus esculentus tiger nut metabolomics UHPLC-ESI-QTOF-MS/MS foodomics scopolamine memory impairments phenol compounds polydatin 3-O-β-d-resveratrol-glucopyranoside cervical cancer lung cancer ovarian cancer nanosuspension antioxidant properties LPS-induced inflammation NO-scavenging activity mountain tea Lamiaceae iridoids phenylethanoids ultrasound-assisted extraction melittoside ajugoside verbascoside ferulic acid apoptosis and cell cycle arrest anti-angiogenesis anti-metastasis synergism Cymbopogon schoenanthus hyaluronidase acetylcholinesterase neurodegeneration skin hair human health immobilized PTP1B drug screening cell surface display salvianolic acid B traditional Chinese medicine Salicornia extraction technologies agro-industrial by-products biological activity circular economy health effects re-integration waste management blood orange peels infrared-assisted extraction optimization Aflatoxin B1 Achillea millefolium bioaccessibility Caco-2 absorption in vitro digestion sterol regulatory element-binding protein 1 human oral squamous cell carcinoma autophagy epidermal fatty acid-binding protein lentil hull enzymatic hydrolysis microwave-assisted extraction oligosaccharides Alocasia gigantea hepatocellular carcinoma histopathology UHPLC–DAD–ESI–MS/MS Salvianolic acid B matrix metalloproteinase 9 gelatinase B MDA-MB-231 human breast cancer cells TIMP-1 agri-food wastes sustainability polyphenols bioavailability polyphenols activity cosmeceuticals nano-delivery health Lithocarpus litseifolius trilobatin phloridzin phloretin metabolic pathway bioactivity honey functional beverage characterization alcoholic beverage fermented beverage functional foods beneficial effects biological treatment bioreactors water aerobic granular sludge conventional active ted sludge biofilter photobioreactor membrane bioreactor bio-electrochemical systems chitosan Indian borage biotic elicitor insect-based foods Folin–Ciocalteu method phenols and flavonoids polyphenols bioactivity cereal pre-harvest sprouting antiradical capacity antitumor activity bee products phenylamides multivariate statistical analysis Juniperus sabina cupressuflavone intranasal pharmacokinetic motor coordination oregano box–behnken phenolics HPLC-PDA analysis UPLC-Q-TOF MS olive pomace PBMC immune gene expression HPLC-DAD metabolome phenolic bioaccessibility propolis total phenolic compounds antioxidant capacity UHPLC-DAD-ESI-MS thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Natural Polyphenols in Human Health |
| title | Natural Polyphenols in Human Health |
| title_full | Natural Polyphenols in Human Health |
| title_fullStr | Natural Polyphenols in Human Health |
| title_full_unstemmed | Natural Polyphenols in Human Health |
| title_short | Natural Polyphenols in Human Health |
| title_sort | natural polyphenols in human health |
| topic | polyphenolic curcumin cisplatin combination therapy breast cancer apoptosis gemini surfactant nanoparticles Mucuna pruriens seed neuroprotective activity Parkinson’s disease anti-acetylcholinesterase activity L-dopa Mitrephora sirikitiae anti-inflammation lignans polyphenols mRNA expression cytokines gemini curcumin colorectal cancer RNA sequencing PPI network differentially expressed genes Ericaceae LC–DAD/ESI–MS phenolic compounds flavonoids antioxidant activity Artemia salina Leach resveratrol hexavalent chromium 8-hydroxydeoxyguanosine adduct repair endogenous antioxidant system antigenotoxic Opuntia sp. prickly pear inflammation ginseng leaf far-infrared irradiation ginsenosides antioxidants health benefits polysaccharides freeze-drying spray-drying antidiabetic Averrhoa carambola L. dihydrochalcone flavone glycosides obesity Oxalidaceae type 2 diabetes Alchemilla viridiflora Rothm. SARS-CoV-2 COVID-19 spike glycoprotein neuropilin-1 in vitro in silico Origanum compactum HPLC-PDA-ESI/MS antibacterial activity bioactive compounds nutraceuticals phenols pomegranate peels phytochemical wistin NADES total polyphenolic content enzyme inhibition functional food natural medicine Alzheimer cholinesterase inhibitors Maqui platelets phenolic compounds and cardiovascular phenolic acids sinapic acid ACE inhibition hypertension endothelial dysfunction Graminex pollen hydroalcoholic extract oxidative stress gene expression TRPV1 pterostilbene antioxidant bioavailability cancer diabetes Nrf2 Rosmarinus officinalis chemical analysis glioblastoma rhabdomyosarcoma red onion phytochemicals H9c2 rat cardiomyoblast primary human fibroblasts blood disorder haemoglobin natural product nutraceutical nutritional disease lichens neuroprotection cetrarioid clade grape polyphenols sarcopenia skeletal muscle clinical trial R. conduplicans lichen secondary metabolites DNA damage α-glucosidase inhibition adlay adlay testa antiglycation phenolic acid grape pomace anti-inflammatory curcumin poly(glycerol sebacate) nanoparticles drug delivery system human cervical cancer baicalein mangiferin quercetin diabetes mellitus peripheral artery disease cardiovascular diseases Cyperus esculentus tiger nut metabolomics UHPLC-ESI-QTOF-MS/MS foodomics scopolamine memory impairments phenol compounds polydatin 3-O-β-d-resveratrol-glucopyranoside cervical cancer lung cancer ovarian cancer nanosuspension antioxidant properties LPS-induced inflammation NO-scavenging activity mountain tea Lamiaceae iridoids phenylethanoids ultrasound-assisted extraction melittoside ajugoside verbascoside ferulic acid apoptosis and cell cycle arrest anti-angiogenesis anti-metastasis synergism Cymbopogon schoenanthus hyaluronidase acetylcholinesterase neurodegeneration skin hair human health immobilized PTP1B drug screening cell surface display salvianolic acid B traditional Chinese medicine Salicornia extraction technologies agro-industrial by-products biological activity circular economy health effects re-integration waste management blood orange peels infrared-assisted extraction optimization Aflatoxin B1 Achillea millefolium bioaccessibility Caco-2 absorption in vitro digestion sterol regulatory element-binding protein 1 human oral squamous cell carcinoma autophagy epidermal fatty acid-binding protein lentil hull enzymatic hydrolysis microwave-assisted extraction oligosaccharides Alocasia gigantea hepatocellular carcinoma histopathology UHPLC–DAD–ESI–MS/MS Salvianolic acid B matrix metalloproteinase 9 gelatinase B MDA-MB-231 human breast cancer cells TIMP-1 agri-food wastes sustainability polyphenols bioavailability polyphenols activity cosmeceuticals nano-delivery health Lithocarpus litseifolius trilobatin phloridzin phloretin metabolic pathway bioactivity honey functional beverage characterization alcoholic beverage fermented beverage functional foods beneficial effects biological treatment bioreactors water aerobic granular sludge conventional active ted sludge biofilter photobioreactor membrane bioreactor bio-electrochemical systems chitosan Indian borage biotic elicitor insect-based foods Folin–Ciocalteu method phenols and flavonoids polyphenols bioactivity cereal pre-harvest sprouting antiradical capacity antitumor activity bee products phenylamides multivariate statistical analysis Juniperus sabina cupressuflavone intranasal pharmacokinetic motor coordination oregano box–behnken phenolics HPLC-PDA analysis UPLC-Q-TOF MS olive pomace PBMC immune gene expression HPLC-DAD metabolome phenolic bioaccessibility propolis total phenolic compounds antioxidant capacity UHPLC-DAD-ESI-MS thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | polyphenolic curcumin cisplatin combination therapy breast cancer apoptosis gemini surfactant nanoparticles Mucuna pruriens seed neuroprotective activity Parkinson’s disease anti-acetylcholinesterase activity L-dopa Mitrephora sirikitiae anti-inflammation lignans polyphenols mRNA expression cytokines gemini curcumin colorectal cancer RNA sequencing PPI network differentially expressed genes Ericaceae LC–DAD/ESI–MS phenolic compounds flavonoids antioxidant activity Artemia salina Leach resveratrol hexavalent chromium 8-hydroxydeoxyguanosine adduct repair endogenous antioxidant system antigenotoxic Opuntia sp. prickly pear inflammation ginseng leaf far-infrared irradiation ginsenosides antioxidants health benefits polysaccharides freeze-drying spray-drying antidiabetic Averrhoa carambola L. dihydrochalcone flavone glycosides obesity Oxalidaceae type 2 diabetes Alchemilla viridiflora Rothm. SARS-CoV-2 COVID-19 spike glycoprotein neuropilin-1 in vitro in silico Origanum compactum HPLC-PDA-ESI/MS antibacterial activity bioactive compounds nutraceuticals phenols pomegranate peels phytochemical wistin NADES total polyphenolic content enzyme inhibition functional food natural medicine Alzheimer cholinesterase inhibitors Maqui platelets phenolic compounds and cardiovascular phenolic acids sinapic acid ACE inhibition hypertension endothelial dysfunction Graminex pollen hydroalcoholic extract oxidative stress gene expression TRPV1 pterostilbene antioxidant bioavailability cancer diabetes Nrf2 Rosmarinus officinalis chemical analysis glioblastoma rhabdomyosarcoma red onion phytochemicals H9c2 rat cardiomyoblast primary human fibroblasts blood disorder haemoglobin natural product nutraceutical nutritional disease lichens neuroprotection cetrarioid clade grape polyphenols sarcopenia skeletal muscle clinical trial R. conduplicans lichen secondary metabolites DNA damage α-glucosidase inhibition adlay adlay testa antiglycation phenolic acid grape pomace anti-inflammatory curcumin poly(glycerol sebacate) nanoparticles drug delivery system human cervical cancer baicalein mangiferin quercetin diabetes mellitus peripheral artery disease cardiovascular diseases Cyperus esculentus tiger nut metabolomics UHPLC-ESI-QTOF-MS/MS foodomics scopolamine memory impairments phenol compounds polydatin 3-O-β-d-resveratrol-glucopyranoside cervical cancer lung cancer ovarian cancer nanosuspension antioxidant properties LPS-induced inflammation NO-scavenging activity mountain tea Lamiaceae iridoids phenylethanoids ultrasound-assisted extraction melittoside ajugoside verbascoside ferulic acid apoptosis and cell cycle arrest anti-angiogenesis anti-metastasis synergism Cymbopogon schoenanthus hyaluronidase acetylcholinesterase neurodegeneration skin hair human health immobilized PTP1B drug screening cell surface display salvianolic acid B traditional Chinese medicine Salicornia extraction technologies agro-industrial by-products biological activity circular economy health effects re-integration waste management blood orange peels infrared-assisted extraction optimization Aflatoxin B1 Achillea millefolium bioaccessibility Caco-2 absorption in vitro digestion sterol regulatory element-binding protein 1 human oral squamous cell carcinoma autophagy epidermal fatty acid-binding protein lentil hull enzymatic hydrolysis microwave-assisted extraction oligosaccharides Alocasia gigantea hepatocellular carcinoma histopathology UHPLC–DAD–ESI–MS/MS Salvianolic acid B matrix metalloproteinase 9 gelatinase B MDA-MB-231 human breast cancer cells TIMP-1 agri-food wastes sustainability polyphenols bioavailability polyphenols activity cosmeceuticals nano-delivery health Lithocarpus litseifolius trilobatin phloridzin phloretin metabolic pathway bioactivity honey functional beverage characterization alcoholic beverage fermented beverage functional foods beneficial effects biological treatment bioreactors water aerobic granular sludge conventional active ted sludge biofilter photobioreactor membrane bioreactor bio-electrochemical systems chitosan Indian borage biotic elicitor insect-based foods Folin–Ciocalteu method phenols and flavonoids polyphenols bioactivity cereal pre-harvest sprouting antiradical capacity antitumor activity bee products phenylamides multivariate statistical analysis Juniperus sabina cupressuflavone intranasal pharmacokinetic motor coordination oregano box–behnken phenolics HPLC-PDA analysis UPLC-Q-TOF MS olive pomace PBMC immune gene expression HPLC-DAD metabolome phenolic bioaccessibility propolis total phenolic compounds antioxidant capacity UHPLC-DAD-ESI-MS thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20231130_9783036590769_284 |