Regulation of Autophagy under Stress
Autophagy is a conserved degradative mechanism essential for cellular homeostasis in eukaryotic organisms. It is a cellular response mechanism that helps cells adapt and survive under various stressful conditions. It involves the degradation and recycling of cellular components to maintain cellular...
-д хадгалсан:
| Формат: | Online |
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| Хэл сонгох: | англи |
| Хэвлэсэн: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Нөхцлүүд: | |
| Онлайн хандалт: | ONIX_20231130_9783036588940_102 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| _version_ | 1863747058875236352 |
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| collection | Directory of Open Access Books |
| description | Autophagy is a conserved degradative mechanism essential for cellular homeostasis in eukaryotic organisms. It is a cellular response mechanism that helps cells adapt and survive under various stressful conditions. It involves the degradation and recycling of cellular components to maintain cellular homeostasis and protect against damage from stressors like nutrient deprivation, oxidative stress, infection, and protein misfolding. However, the understanding of the molecular mechanisms of autophagy regulation is still in significant development, including the involvement of gasotransmitters and small signaling molecules, such as those produced under ROS, RNS and RSS. Dysregulation of autophagy has been implicated in various diseases, making it an important area of research to improve biomedical therapies and strategies for overcoming the challenges from environmental stresses. Therefore, this Special Issue aims to review the current developments regarding autophagy research. |
| format | Online |
| id | doab-20.500.12854ir-128650 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1286502024-04-11T15:11:13Z Regulation of Autophagy under Stress Aroca, Angeles Gotor, Cecilia mitophagy aging Reactive Oxygen Species PINK1 mitochondria Alzheimer Parkinson melatonin metabolic syndrome autophagy lipophagy Harderian gland degradation vacuole autophagosomes autophagy-related protein energy stress ER stress nutrient stress oxidative stress regulation autophagy-related genes (ATG) hydrogen sulfide persulfidation OXPHOS mitochondrial diseases Harlequin heart skeletal muscle cerebellum brain ULK1 CHK2 ROS mTOR AMD DR glaucoma hypoxia inflammation rapamycin clinical trial intestinal homeostasis colorectal cancer stress response GPCR Gq mechanotransduction extracellular matrix non-alcoholic fatty liver disease stevia stevioside PPARα thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Autophagy is a conserved degradative mechanism essential for cellular homeostasis in eukaryotic organisms. It is a cellular response mechanism that helps cells adapt and survive under various stressful conditions. It involves the degradation and recycling of cellular components to maintain cellular homeostasis and protect against damage from stressors like nutrient deprivation, oxidative stress, infection, and protein misfolding. However, the understanding of the molecular mechanisms of autophagy regulation is still in significant development, including the involvement of gasotransmitters and small signaling molecules, such as those produced under ROS, RNS and RSS. Dysregulation of autophagy has been implicated in various diseases, making it an important area of research to improve biomedical therapies and strategies for overcoming the challenges from environmental stresses. Therefore, this Special Issue aims to review the current developments regarding autophagy research. 2023-11-30T20:40:27Z 2023-11-30T20:40:27Z 2023 book ONIX_20231130_9783036588940_102 9783036588940 9783036588957 https://directory.doabooks.org/handle/20.500.12854/128650 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8102 https://mdpi.com/books/pdfview/book/8102 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8895-7 10.3390/books978-3-0365-8895-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036588940 9783036588957 232 Basel open access |
| spellingShingle | mitophagy aging Reactive Oxygen Species PINK1 mitochondria Alzheimer Parkinson melatonin metabolic syndrome autophagy lipophagy Harderian gland degradation vacuole autophagosomes autophagy-related protein energy stress ER stress nutrient stress oxidative stress regulation autophagy-related genes (ATG) hydrogen sulfide persulfidation OXPHOS mitochondrial diseases Harlequin heart skeletal muscle cerebellum brain ULK1 CHK2 ROS mTOR AMD DR glaucoma hypoxia inflammation rapamycin clinical trial intestinal homeostasis colorectal cancer stress response GPCR Gq mechanotransduction extracellular matrix non-alcoholic fatty liver disease stevia stevioside PPARα thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Regulation of Autophagy under Stress |
| title | Regulation of Autophagy under Stress |
| title_full | Regulation of Autophagy under Stress |
| title_fullStr | Regulation of Autophagy under Stress |
| title_full_unstemmed | Regulation of Autophagy under Stress |
| title_short | Regulation of Autophagy under Stress |
| title_sort | regulation of autophagy under stress |
| topic | mitophagy aging Reactive Oxygen Species PINK1 mitochondria Alzheimer Parkinson melatonin metabolic syndrome autophagy lipophagy Harderian gland degradation vacuole autophagosomes autophagy-related protein energy stress ER stress nutrient stress oxidative stress regulation autophagy-related genes (ATG) hydrogen sulfide persulfidation OXPHOS mitochondrial diseases Harlequin heart skeletal muscle cerebellum brain ULK1 CHK2 ROS mTOR AMD DR glaucoma hypoxia inflammation rapamycin clinical trial intestinal homeostasis colorectal cancer stress response GPCR Gq mechanotransduction extracellular matrix non-alcoholic fatty liver disease stevia stevioside PPARα thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology |
| topic_facet | mitophagy aging Reactive Oxygen Species PINK1 mitochondria Alzheimer Parkinson melatonin metabolic syndrome autophagy lipophagy Harderian gland degradation vacuole autophagosomes autophagy-related protein energy stress ER stress nutrient stress oxidative stress regulation autophagy-related genes (ATG) hydrogen sulfide persulfidation OXPHOS mitochondrial diseases Harlequin heart skeletal muscle cerebellum brain ULK1 CHK2 ROS mTOR AMD DR glaucoma hypoxia inflammation rapamycin clinical trial intestinal homeostasis colorectal cancer stress response GPCR Gq mechanotransduction extracellular matrix non-alcoholic fatty liver disease stevia stevioside PPARα thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology |
| url | ONIX_20231130_9783036588940_102 |