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Pathogenesis and Novel Therapeutics in Asthma

Asthma is a prevalent chronic inflammatory disease of the airways with complex etiology and mechanistic pathways and variable clinical presentation. Such heterogeneity renders the search for targeted therapies difficult. Currently, the best-known disease phenotype with tailored biological treatment...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
bronchial epithelial cells
extracellular vesicles
miRNAs
airway epithelium
asthma
cellular compartmentalization
allergic rhinitis
allergen immunotherapy
bronchial asthma
component-resolved diagnosis
sublingual immunotherapy
fungal sensitization
IL-17A
Candida albicans
mediation effect
oxidative stress
CBA assay
airway remodeling
severe asthma
bronchial fibroblasts
fibrosis
Bcl10
NF-κB pathway
cytokines
efficacy
investigational
Phase I
Phase II
RCT
allergy
eosinophils
immune health
natural therapeutics
prostacyclin
allergic inflammation
proinflammatory
anti-inflammatory
BLT2
G-CSF
12-LO
neutrophil
airway inflammation
n/a
miRNA
children
serum
exhaled breath condensate
diagnosis
exacerbation
biomarkers
factors
thema EDItEUR::M Medicine and Nursing
Online Access:ONIX_20230714_9783036578422_21
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