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Oncogenic Signaling of Growth Factor Receptors in Cancer: Mechanisms and Therapeutic Opportunities

At the molecular level, the activation of growth factor receptors (GFRs) induces a mitogenic response and maintains cancer cell growth. The majority of malignant diseases are related to aberrant intra- and intercellular communication, associated with the GFR-mediated pathways. Moreover, the evasion...

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Format: Online
Jezik:angleščina
Izdano: MDPI - Multidisciplinary Digital Publishing Institute 2023
Teme:
oral cancer
autophagy
PI3K/AKT/mTOR signaling pathway
gastric cancer
HER3
heregulin
MET
SATB1
breast cancer
estrogen receptor-positive
HER2
PI3K/AKT/mTOR pathway
endocrine resistance
glioma
pathways
EGFR
clinical trials
gastric carcinoma
norepinephrine transporter
plasma free metanephrines and normetanephrines
coronavirus
pandemic
tyrosine kinase
receptor
signaling pathway
ELTD1
biomarker
angiogenesis
cancer
colorectal cancer
growth factors
PI3K/AKT/mTOR
MAPK
growth factor inhibitors
nivolumab
interleukin 10
T cells
cytokines
STAT3 pathway
AKT serine–threonine kinase pathway
MAP kinase pathway
single-cell RNA-seq
primary cerebral tumors
cancer stem-like cells
human neural stem cells
human neural progenitors
neurogenesis
gliogenesis
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Online dostop:ONIX_20230511_9783036573373_107
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