Hydrogels in Regenerative Medicine and Other Biomedical Applications

Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogels usually consist of three-dimensional matrices of hydrophilic polymers, held together by chemical or physical crosslinks, or supramolecular assemblies of small amphiphilic mol...

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Publicado: MDPI - Multidisciplinary Digital Publishing Institute 2023
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description Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogels usually consist of three-dimensional matrices of hydrophilic polymers, held together by chemical or physical crosslinks, or supramolecular assemblies of small amphiphilic molecules. The gelation process occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light, and others. Consisting of mainly water molecules, they represent a unique class of materials, with many applications such as cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, and 3D bioprinting. Despite these great strides, there is still much more to discover in this area. This Special Issue is focused on the use of hydrogels in tissue and bone regeneration. Hydrogels are particularly suited for this purpose as their physical characteristics resemble that of the extracellular matrix; as such, they have found applications as an extracellular medium for cancer cells, stem cells, and neuronal cells. This Special Issue also includes research papers on the other biomedical applications of hydrogels.
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spelling doab-20.500.12854ir-1000092024-04-11T15:11:12Z Hydrogels in Regenerative Medicine and Other Biomedical Applications Jervis, Peter John polyvinyl alcohol cobalt-substituted hydroxyapatite diabetic foot ulcers hydrogels antibacterial ability chitosan cellulose hydrogel wound dressings burn wounds diabetic wounds chronic wounds acute wounds methacrylate glycol chitosan beta-cyclodextrin triclosan antibacterial tissue bio-adhesive poly(2-hydroxyethyl methacrylate) 3D scaffold RGDS chronic lymphocytic leukemia B cell survival synthetic mimic of heparin poly(sodium-4-styrenesulfonate) myoblast myogenic differentiation fusion focal adhesion kinase (FAK) supramolecular dehydrodipeptide drug delivery wound healing cancer smart materials peptidomimetic 3d printing PLCL decellularization angiogenesis dECM hydrogel adipose tissue regeneration entrapment neuropathy animal model ultrasound carpal tunnel syndrome alginate PNIPAM-based graft copolymers thermo-responsive shear-responsive LCST adjustment sol–gel transition rheological properties injectability poly(vinyl alcohol) decellularized cartilage matrix bioprinting thiol-ene cross-linking sodium alginate betamethasone cartilage tissue engineering testicular tissue transplantation fertility preservation VEGF PDGF vascular maturity necrosis inhibitor spermatogonia stem cells nanoparticles tissue engineering functionalization Chit-HVP Chit-RGD XPS NEXAFS h-osteoblasts tunable lens ultrasonic detection deep detection phononic crystal PVA marjoram oil kaolin hemostatic dressing antibacterial and antioxidant wound dressing human hair keratin fibrinogen injectable hydrogel human gingival fibroblast biomaterials biocompatibility in vitro model hybrid hydrogel extracellular matrix microenvironment mimicking matrix n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogels usually consist of three-dimensional matrices of hydrophilic polymers, held together by chemical or physical crosslinks, or supramolecular assemblies of small amphiphilic molecules. The gelation process occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light, and others. Consisting of mainly water molecules, they represent a unique class of materials, with many applications such as cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, and 3D bioprinting. Despite these great strides, there is still much more to discover in this area. This Special Issue is focused on the use of hydrogels in tissue and bone regeneration. Hydrogels are particularly suited for this purpose as their physical characteristics resemble that of the extracellular matrix; as such, they have found applications as an extracellular medium for cancer cells, stem cells, and neuronal cells. This Special Issue also includes research papers on the other biomedical applications of hydrogels. 2023-05-11T17:16:29Z 2023-05-11T17:16:29Z 2023 book ONIX_20230511_9783036572512_26 9783036572512 9783036572505 https://directory.doabooks.org/handle/20.500.12854/100009 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7102 https://mdpi.com/books/pdfview/book/7102 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7250-5 10.3390/books978-3-0365-7250-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036572512 9783036572505 358 Basel open access
spellingShingle polyvinyl alcohol
cobalt-substituted hydroxyapatite
diabetic foot ulcers
hydrogels
antibacterial ability
chitosan
cellulose
hydrogel
wound dressings
burn wounds
diabetic wounds
chronic wounds
acute wounds
methacrylate glycol chitosan
beta-cyclodextrin
triclosan
antibacterial
tissue bio-adhesive
poly(2-hydroxyethyl methacrylate)
3D scaffold
RGDS
chronic lymphocytic leukemia
B cell survival
synthetic mimic of heparin
poly(sodium-4-styrenesulfonate)
myoblast
myogenic differentiation
fusion
focal adhesion kinase (FAK)
supramolecular
dehydrodipeptide
drug delivery
wound healing
cancer
smart materials
peptidomimetic
3d printing
PLCL
decellularization
angiogenesis
dECM hydrogel
adipose tissue regeneration
entrapment neuropathy
animal model
ultrasound
carpal tunnel syndrome
alginate
PNIPAM-based graft copolymers
thermo-responsive
shear-responsive
LCST adjustment
sol–gel transition
rheological properties
injectability
poly(vinyl alcohol)
decellularized cartilage matrix
bioprinting
thiol-ene cross-linking
sodium alginate
betamethasone
cartilage tissue engineering
testicular tissue transplantation
fertility preservation
VEGF
PDGF
vascular maturity
necrosis inhibitor
spermatogonia stem cells
nanoparticles
tissue engineering
functionalization
Chit-HVP
Chit-RGD
XPS
NEXAFS
h-osteoblasts
tunable lens
ultrasonic detection
deep detection
phononic crystal
PVA
marjoram oil
kaolin
hemostatic dressing
antibacterial and antioxidant wound dressing
human hair keratin
fibrinogen
injectable hydrogel
human gingival fibroblast
biomaterials
biocompatibility
in vitro model
hybrid hydrogel
extracellular matrix
microenvironment mimicking matrix
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
Hydrogels in Regenerative Medicine and Other Biomedical Applications
title Hydrogels in Regenerative Medicine and Other Biomedical Applications
title_full Hydrogels in Regenerative Medicine and Other Biomedical Applications
title_fullStr Hydrogels in Regenerative Medicine and Other Biomedical Applications
title_full_unstemmed Hydrogels in Regenerative Medicine and Other Biomedical Applications
title_short Hydrogels in Regenerative Medicine and Other Biomedical Applications
title_sort hydrogels in regenerative medicine and other biomedical applications
topic polyvinyl alcohol
cobalt-substituted hydroxyapatite
diabetic foot ulcers
hydrogels
antibacterial ability
chitosan
cellulose
hydrogel
wound dressings
burn wounds
diabetic wounds
chronic wounds
acute wounds
methacrylate glycol chitosan
beta-cyclodextrin
triclosan
antibacterial
tissue bio-adhesive
poly(2-hydroxyethyl methacrylate)
3D scaffold
RGDS
chronic lymphocytic leukemia
B cell survival
synthetic mimic of heparin
poly(sodium-4-styrenesulfonate)
myoblast
myogenic differentiation
fusion
focal adhesion kinase (FAK)
supramolecular
dehydrodipeptide
drug delivery
wound healing
cancer
smart materials
peptidomimetic
3d printing
PLCL
decellularization
angiogenesis
dECM hydrogel
adipose tissue regeneration
entrapment neuropathy
animal model
ultrasound
carpal tunnel syndrome
alginate
PNIPAM-based graft copolymers
thermo-responsive
shear-responsive
LCST adjustment
sol–gel transition
rheological properties
injectability
poly(vinyl alcohol)
decellularized cartilage matrix
bioprinting
thiol-ene cross-linking
sodium alginate
betamethasone
cartilage tissue engineering
testicular tissue transplantation
fertility preservation
VEGF
PDGF
vascular maturity
necrosis inhibitor
spermatogonia stem cells
nanoparticles
tissue engineering
functionalization
Chit-HVP
Chit-RGD
XPS
NEXAFS
h-osteoblasts
tunable lens
ultrasonic detection
deep detection
phononic crystal
PVA
marjoram oil
kaolin
hemostatic dressing
antibacterial and antioxidant wound dressing
human hair keratin
fibrinogen
injectable hydrogel
human gingival fibroblast
biomaterials
biocompatibility
in vitro model
hybrid hydrogel
extracellular matrix
microenvironment mimicking matrix
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
topic_facet polyvinyl alcohol
cobalt-substituted hydroxyapatite
diabetic foot ulcers
hydrogels
antibacterial ability
chitosan
cellulose
hydrogel
wound dressings
burn wounds
diabetic wounds
chronic wounds
acute wounds
methacrylate glycol chitosan
beta-cyclodextrin
triclosan
antibacterial
tissue bio-adhesive
poly(2-hydroxyethyl methacrylate)
3D scaffold
RGDS
chronic lymphocytic leukemia
B cell survival
synthetic mimic of heparin
poly(sodium-4-styrenesulfonate)
myoblast
myogenic differentiation
fusion
focal adhesion kinase (FAK)
supramolecular
dehydrodipeptide
drug delivery
wound healing
cancer
smart materials
peptidomimetic
3d printing
PLCL
decellularization
angiogenesis
dECM hydrogel
adipose tissue regeneration
entrapment neuropathy
animal model
ultrasound
carpal tunnel syndrome
alginate
PNIPAM-based graft copolymers
thermo-responsive
shear-responsive
LCST adjustment
sol–gel transition
rheological properties
injectability
poly(vinyl alcohol)
decellularized cartilage matrix
bioprinting
thiol-ene cross-linking
sodium alginate
betamethasone
cartilage tissue engineering
testicular tissue transplantation
fertility preservation
VEGF
PDGF
vascular maturity
necrosis inhibitor
spermatogonia stem cells
nanoparticles
tissue engineering
functionalization
Chit-HVP
Chit-RGD
XPS
NEXAFS
h-osteoblasts
tunable lens
ultrasonic detection
deep detection
phononic crystal
PVA
marjoram oil
kaolin
hemostatic dressing
antibacterial and antioxidant wound dressing
human hair keratin
fibrinogen
injectable hydrogel
human gingival fibroblast
biomaterials
biocompatibility
in vitro model
hybrid hydrogel
extracellular matrix
microenvironment mimicking matrix
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
url ONIX_20230511_9783036572512_26