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Quantitative Assessment and Validation of Network Inference Methods in Bioinformatics
Publicado 2021“...One of the major challenges of the post-genomic era is to extract functional information by integrating such heterogeneous high-throughput genomic data. ...”
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Radiopharmaceutical Chemistry between Imaging and Endoradiotherapy
Publicado 2021“...Radiolabelled molecules, bearing a “radioactive lantern”, function as so called Radiopharmaceuticals which have to be compliant with the pharmaceuticals act, and can be termed as “food” of nuclear medicine. ...”
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Re-Enacting Sensorimotor Experience for Cognition
Publicado 2021“...Empirical investigation on the functioning of similar processes in the brain and on their implementation in artificial agents is fragmented. ...”
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Recent Advances in Mechanics of Non-Newtonian Fluids
Publicado 2021Subjects: “...marginal function...”
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Recent Advances in Symbiosis Research: Integrative Approaches
Publicado 2021“...Traditionally, symbiosis research has been undertaken by researchers working independently of one another and often focused on a few cases of bipartite host-symbiont interactions. New model systems are emerging that will enable us to fill fundamental gaps in symbiosis research and theory, focusing on a broad range of symbiotic interactions and including a variety of multicellular hosts and their complex microbial communities. ...”
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Recent Advances of Epigenetics in Crop Biotechnology
Publicado 2021“...DNA methylation, histone modifications and small RNAs have been identified, and their functions are being studied in order to understand the mechanisms of interaction and regulation among the different biological processes in plants. ...”
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Recent Progress in Bunyavirus Research
Publicado 2021“...Although all bunyaviruses possesses a tripartite, negative-sense (or ambi-sense) RNA genome, they exhibit substantial differences in their structure, genome organization and replication strategies, which make functional interpolation across genus boundaries difficult. ...”
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Regulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease Kinases, GTPases and ATPases
Publicado 2021“...Interestingly, a number of PD proteins have enzymatic functions, including kinase, GTPase or ATPase functions. ...”
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Regulation by non-coding RNAs
Publicado 2021“...The bacterial and archeal immune system CRISPR, and the eukaryotic piwi-interacting RNAs (piRNA) immune system that inhibits mobile elements in germ line cells both function by via RNA transcript/ target DNA heteroduplex base-pairing are a specific class of RNAs that protect cells from invading transposons/and or viruses. siRNAs function in plant and invertebrate immune systems and protect against viral infections. [...]...”
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Regulation by non-coding RNAs
Publicado 2021“...The bacterial and archeal immune system CRISPR, and the eukaryotic piwi-interacting RNAs (piRNA) immune system that inhibits mobile elements in germ line cells both function by via RNA transcript/ target DNA heteroduplex base-pairing are a specific class of RNAs that protect cells from invading transposons/and or viruses. siRNAs function in plant and invertebrate immune systems and protect against viral infections. [...]...”
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The regulation of angiogenesis by tissue cell-macrophage interactions
Publicado 2021“...Macrophages exhibit high plasticity and are capable of shifting between different activation modes and functions according to their changing microenvironment. ...”
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Regulation of Chemokine- Receptor Interactions and Functions
Publicado 2021“...Extensive research has revealed that the functions of chemokines and their receptors are regulated at numerous levels, including: genetic mutations/polymorphisms; control of expression levels; ligand internalization via functional or decoy receptors; intrinsic selectivity of chemokine-receptor binding; hetero- or homo-oligomerization of chemokines or of receptors; alternative signalling pathways; interaction of chemokines with glycosaminoglycans; post-translational modifications; and binding to pathogen-derived inhibitors. ...”
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Regulation of immune system cell functions by protein kinase C
Publicado 2021“...Most PKC proteins are ubiquitously expressed and participate in a plethora of functions in most cell types. A majority of PKC isoforms is also expressed in cells of the immune system in which they are involved in signal transduction downstream of a range of surface receptors, including the antigen receptors on T and B lymphocytes. ...”
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Regulatory Stewardship of Health Research: Navigating Participant Protection and Research Promotion
Publicado 2021“...This timely book examines the interaction of health research and regulation with law through empirical analysis and the application of key anthropological concepts to reveal the inner workings of human health research. ...”
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Rethinking the Internet of Things: A Scalable Approach to Connecting Everything
Publicado 2021“...An architecture comprised of integrator functions, propagator nodes, and end devices, along with their interactions, is explored....”
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Reversible Ubiquitylation in Plant Biology
Publicado 2021“...Post-translational modification of proteins by reversible ubiquitylation could drastically affects the modified proteins by proteolytic processing and turnover, altering catalytic activity, subcellular targeting, and protein-protein interaction. Continued efforts are being carried out to identify novel substrates critical for various cellular and organismal processes, to determine effects of reversible ubiquitylation on the modified substrates, to determine signaling determinants triggering reversible ubiquitylation of specific substrates, to illustrate individual components of the ubiquitin system for their in vivo functions and involved mechanistic roles, and to determine mechanistic roles of modification acting on critical components of major cellular processes and regulatory mechanisms. ...”
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Reward- and aversion-related processing in the brain: translational evidence for separate and shared circuits
Publicado 2021“...Moreover, we do we yet understand how they interact anatomically or functionally. The aim of the current project was to gather some translational evidence to help clarify the role of such circuits. ...”
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Role of DNA Methyltransferases in the Epigenome
Publicado 2021“...Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. ...”
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